Ritu N Swali, Blanca Estupiñan, Emily L Guo, Heather Richmond, Paul M Friedman
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引用次数: 0
摘要
背景:太田痣(NOTA太田痣(NOTA)是幼年或妊娠期获得的真皮黑素细胞增多症。由于太田痣的颜色多变,通常需要结合多种波长才能成功治疗。质量开关激光在针对真皮色素方面一直显示出疗效,而皮秒激光(PSL)则是治疗色素性疾病的新兴技术:为进一步阐明其疗效,作者对 2021 年至 2023 年间使用 785 纳米 PSL 治疗棕色 NOTA 病变的 17 名 NOTA 患者进行了回顾性研究:主要终点是根据由 3 位经委员会认证的皮肤科医生使用五点视觉模拟量表审查的前后照片分析临床改善情况:本研究共纳入了 17 名菲茨帕特里克皮肤类型 (FST) II 至 V 的患者,他们的年龄从 14 岁到 38 岁不等。患者平均接受了 3.2 次治疗,每次间隔 2 至 3 个月。视觉模拟评分显示,平均清除率为 51% 至 75%。没有发现色素改变:由于NOTA在较高的FST中很常见,作者认为785纳米PSL是治疗这些皮肤类型中棕色NOTA的极佳选择。这项研究强调了进一步研究的必要性,以确定基于颜色的激光治疗 NOTA 方法的最佳治疗参数。
Efficacy of 785-nm Picosecond Titanium Sapphire Laser for Treatment of Brown Nevus of Ota Lesions in FST II-V: A Retrospective Analysis.
Background: Nevus of Ota (NOTA) is a dermal melanocytosis acquired in early childhood or pregnancy. Given their color variability, NOTA often require a combination of wavelengths for successful treatment. Quality-switched lasers have consistently shown efficacy in targeting dermal pigment, while picosecond lasers (PSLs) are an emerging technology for pigmentary disorders.
Objective: To further elucidate its efficacy, the authors conducted a retrospective review of 17 patients with NOTA treated with a 785-nm PSL for brown NOTA lesions between 2021 and 2023.
Materials and methods: The primary end point analyzed clinical improvement based on before and after photography reviewed by 3 board-certified dermatologists using a five-point visual analog scale.
Results: Seventeen patients of Fitzpatrick skin types (FSTs) II to V, ranging from ages 14 to 38 years, were included in this study. Patients were treated for an average of 3.2 sessions in 2 to 3-month intervals. Visual analog scale scores demonstrated a mean clearance of 51% to 75%. No pigmentary alterations were noted.
Conclusion: Because NOTA is common in higher FSTs, the authors believe that the 785-nm PSL is an excellent treatment option for brown NOTA in these skin types. This study highlights the need for further investigation to determine optimal treatment parameters for the color-based laser treatment approach for NOTA.
期刊介绍:
Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including:
-Ambulatory phlebectomy-
Blepharoplasty-
Body contouring-
Chemical peels-
Cryosurgery-
Curettage and desiccation-
Dermabrasion-
Excision and closure-
Flap Surgery-
Grafting-
Hair restoration surgery-
Injectable neuromodulators-
Laser surgery-
Liposuction-
Microdermabrasion-
Microlipoinjection-
Micropigmentation-
Mohs micrographic surgery-
Nail surgery-
Phlebology-
Sclerotherapy-
Skin cancer surgery-
Skin resurfacing-
Soft-tissue fillers.
Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.