头孢他啶在中枢神经系统和眼部感染中的应用:病例系列。

IF 3.7 Q2 INFECTIOUS DISEASES JAC-Antimicrobial Resistance Pub Date : 2024-06-17 eCollection Date: 2024-06-01 DOI:10.1093/jacamr/dlae095
Emily A Siegrist, Joseph Sassine
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引用次数: 0

摘要

背景:描述头孢他啶治疗中枢神经系统或眼部受累感染患者疗效的数据有限:描述头孢他啶治疗中枢神经系统或眼部受累感染患者疗效的数据有限:描述中枢神经系统或眼部受累的耐甲氧西林葡萄球菌感染患者接受头孢他啶治疗的疗效:这是一项回顾性研究,研究对象是一家学术医疗中心的10名因中枢神经系统或眼部感染而接受头孢他啶治疗的患者:结果:所有患者都接受了头孢他啶治疗,作为抢救治疗的联合用药。四名患者死亡,六名患者临床治愈。只有一名患者出现微生物复发:这些初步数据表明,头孢他啶在联合使用时可能是严重葡萄球菌感染抢救治疗的一种选择。
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Ceftaroline in CNS and ocular infections: a case series.

Background: There are limited data describing outcomes of patients treated with ceftaroline for infections with CNS or ocular involvement.

Objectives: To describe outcomes of patients treated with ceftaroline for methicillin-resistant staphylococcal infections involving the CNS or eye.

Patients and methods: This was a retrospective review of 10 patients at an academic medical centre who received ceftaroline for CNS or ocular infections.

Results: All patients were treated with ceftaroline as part of a combination for salvage therapy. Four patients died, whereas six patients experienced clinical cure. Only one experienced microbiological recurrence.

Conclusions: These preliminary data suggest that ceftaroline may be an option for salvage therapy of severe staphylococcal infections when used in combination.

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来源期刊
CiteScore
5.30
自引率
0.00%
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审稿时长
16 weeks
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