钙化评分与腹主动脉瘤血管内修复结果的相关性

Vascular and endovascular surgery Pub Date : 2024-10-01 Epub Date: 2024-06-17 DOI:10.1177/15385744241263696
Houssam Farres, Santh Prakash Lanka, Sam Nussbaum, Mira Shoukry, Tareq Hanouneh, Lauren Alexander, David Sella, Tambi Jarmi
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引用次数: 0

摘要

目的:血管内动脉瘤修补术虽然是微创手术,而且围手术期并发症发生率相对较低,但与内漏相关的长期再介入率却很高。研究发现,有几个变量可以预测血管内动脉瘤修补术的结果,其中之一就是血管的钙负荷。这促使我们研究用标准化的阿加斯顿评分系统测量的钙负荷与血管内动脉瘤修补术结果之间的关联:这是一项回顾性研究,研究对象是 2008 年至 2020 年期间在我院接受血管内动脉瘤修补术的患者,术前进行了非对比度计算机断层扫描,共 87 例患者。血管的钙质负荷是通过Agatston评分系统进行测量的,该系统具有更好的可重复性,结果变量包括死亡率和内漏:结果:与无2型内膜渗漏的患者相比,中位总钙评分较高(≥12966.9)的患者五年后的生存率明显较低(79.8% vs 52.3% (P = .002)),而中位总钙评分较低的患者五年后的生存率较高(P = .05):结论:使用标准化的阿加斯顿评分系统得出的钙评分可作为死亡率风险的预测指标,有助于决定患者的治疗方案。
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Correlation Between Calcium Scoring and Abdominal Aortic Aneurysm Endovascular Repair Outcomes.

Objectives: Endovascular aneurysm repair, though minimally invasive and has the benefit of relatively low perioperative complication rates, it is associated with significant long term reintervention rates related to endoleaks. Several variables have been studied to predict the outcomes of endovascular aneurysm repair, 1 of which is the calcium burden of the vasculature. This prompted us to study the association between calcium burden measured by the standardized Agatston scoring system and the outcomes of Endovascular aneurysm repair.

Methods: This is a retrospective study of patients who underwent Endovascular aneurysm repair from 2008 to 2020 at our institution and who had a non-contrast computerized tomography scan preoperatively, accounting for 87 patients. The calcium burden of the vasculature was measured by the Agatston scoring system allowing for better reproducibility, and the outcome variables included mortality and endoleaks.

Results: Patients with higher median total calcium scores (≥12966.9) had significantly lesser survival (79.8% vs 52.3% (P = .002) at five years compared to patients with lower median total calcium score (<12966.9). Also, patients with type 2 endoleaks had higher calcium scores in above the aneurysm level ((1591.2 vs 688.2), P = .05)) compared to patients with no type 2 endoleaks.

Conclusion: Calcium score assigned using a standardized Agatston scoring system can be used as a predictor of mortality risk assisting in deciding the treatment of choice for patients.

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