2 型炎症疾病的发病率和并存性。

IF 4.6 2区医学 Q2 ALLERGY Clinical and Translational Allergy Pub Date : 2024-06-19 DOI:10.1002/clt2.12376

Toni Mora, Irene Sánchez-Collado, Rosa Muñoz-Cano, Paula Ribó, Paloma I. Palomo-Jiménez, Joaquim Mullol, Antonio Valero

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引用次数: 0

摘要

背景：2型炎症已被描述为特应性皮炎（AD）、慢性鼻炎伴鼻息肉和哮喘（CRSwNP）等一些疾病的共同病理生理基础：本研究利用加泰罗尼亚地区的人群发病率，分析了主要诊断为上述疾病的患者同时患有 2 型炎症的情况：结果：我们发现，这些患者中同时患有 2 型炎症疾病的比例很高，其中除 AD 外，其他严重疾病的患病率更高。在原发性疾病的严重类型中，合并 2 型炎症疾病（严重或不严重）的患者比例分别为：AD 16.2%、哮喘 19.8%、CRSwNP 62.4%。该患者人群中同时患有2型炎症疾病的比例最高，包括重症（48.9%）和非重症（13.5%）：结论：我们的研究结果对AD、哮喘和CRSwNP患者的管理具有重要意义。

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Prevalence and coexistence of type 2 inflammatory diseases

Background

Type 2 inflammation has been described as a pathophysiological basis common to some diseases, such as atopic dermatitis (AD), chronic rhinosinusitis with nasal polyps, and asthma (CRSwNP).

Objective

The present study used population-based prevalence in Catalonia to analyse the coexistence of type 2 inflammatory diseases in patients primarily diagnosed with the above mentioned conditions.

Results

We found a high degree of coexistence of type 2 inflammatory diseases among these patients, with the prevalence being higher in the severe forms, except for AD. For the severe forms of primary diseases, the proportion of patients with coexisting type 2 inflammatory diseases (severe or non-severe) was 16.2% for AD, 19.8% for asthma, and a striking 62.4% for CRSwNP. This patient population has the highest proportion of coexisting type 2 inflammatory diseases, both severe (48.9%) and non-severe (13.5%).

Conclusion

Our findings have significant implications for the management of patients with AD, asthma, and CRSwNP.

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来源期刊

Clinical and Translational Allergy Immunology and Microbiology-Immunology

CiteScore

7.50

自引率

4.50%

发文量

117

审稿时长

12 weeks

期刊介绍： Clinical and Translational Allergy, one of several journals in the portfolio of the European Academy of Allergy and Clinical Immunology, provides a platform for the dissemination of allergy research and reviews, as well as EAACI position papers, task force reports and guidelines, amongst an international scientific audience. Clinical and Translational Allergy accepts clinical and translational research in the following areas and other related topics: asthma, rhinitis, rhinosinusitis, drug hypersensitivity, allergic conjunctivitis, allergic skin diseases, atopic eczema, urticaria, angioedema, venom hypersensitivity, anaphylaxis, food allergy, immunotherapy, immune modulators and biologics, animal models of allergic disease, immune mechanisms, or any other topic related to allergic disease.