比较四个欧洲国家实施长效丁丙诺啡治疗布维达的情况。

Expert opinion on drug delivery Pub Date : 2024-05-01 Epub Date: 2024-06-19 DOI:10.1080/17425247.2024.2369756
Benjamin Rolland, Catriona Matheson, Ari Kaski, Margaux Kosim, Carlos Roncero, Florence Vorspan
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引用次数: 0

摘要

背景:Buvidal是目前欧洲唯一的去势丁丙诺啡。Buvidal提供了一种新的治疗模式,可能需要对阿片激动剂治疗(OATs)的国家监管框架以及国家护理系统进行一些调整:研究设计与方法:通过定性调查,比较了英国、芬兰、西班牙和法国在全国范围内布韦达的推广情况、治疗人群的类型、国家监管框架以及布韦达实施的护理组织系统等方面的数据:2022年,英国接受OAT治疗的患者中接受布维达治疗的比例为2.1%,芬兰为60-65%,西班牙为1%,法国为0.3%。在芬兰和英国,药物费用由国家医疗系统承担,而在西班牙和法国,Buvidal 只能在专业中心使用,其费用必须由专业中心承担。其他国家的特点也可能是造成布维达使用率差距的原因,包括 OAT 的基线覆盖水平,法国和西班牙的 OAT 覆盖率都很高:结论:在使用 OAT 的人群中,Buvidal 在各国的推广情况存在重大差异。
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Compared implementation of the long-acting buprenorphine treatment buvidal in four European countries.

Background: Buvidal is the only depot buprenorphine currently available in Europe. Buvidal offers a new treatment paradigm, which may require some adjustment in the national regulatory frameworks for opioid agonist treatments (OATs), as well as the national care systems.

Research design and methods: Data on the national dissemination of Buvidal, types of populations treated, and the national regulatory framework and care organization system through which Buvidal has been implemented were compared between the UK, Finland, Spain, and France, using a qualitative survey.

Results: In 2022, the proportion of people on OAT who received Buvidal was 2.1% in the UK, 60-65% in Finland, 1% in Spain, and 0.3% in France. In both Finland and the UK, the cost of the medication is covered by the national health system, whereas, in Spain and France, Buvidal is accessible only in specialized centers, which must carry its cost. Other national features may explain the gaps in Buvidal use, including the baseline level of OAT coverage, which was high in both France and Spain.

Conclusions: Important national discrepancies are found regarding Buvidal dissemination among people on OAT.

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