重铬酸钾敏感表现为特非林皮炎:一项回顾性队列研究。

IF 5.4 3区 材料科学 Q2 CHEMISTRY, PHYSICAL ACS Applied Energy Materials Pub Date : 2024-06-24 DOI:10.1111/cod.14627
Daniel Hilewitz, Akiva Trattner, Yehonatan Noyman, Daniel Mimouni, Igor Snast
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引用次数: 0

摘要

背景介绍特非林是犹太男子在日常祈祷时佩戴的宗教用品。由于对重铬酸钾敏感而继发的特非林皮炎已得到认可,但相关数据仍然很少:目的:调查特菲林皮炎的发病率和临床特征:方法:在一家三级皮肤病诊所对 2009-2023 年期间接受欧洲基线系列贴片测试并被诊断为特非林皮炎的患者进行档案审查,并记录他们的临床数据:在连续接受检测的 1679 名男性患者中,有 25 人(1.49%)被诊断为特非林皮炎,占所有重铬酸钾阳性患者(163/1679)的 15.34%。症状出现前使用特非林的平均时间为 38 ± 16.9 年,平均随访时间为 3.1 ± 2.9 年。患者在直接接触到皮盒或皮带的身体部位出现湿疹。32%的患者出现了id反应,44%的患者对其他皮革配件敏感。14名患者(56%)改用不含铬酸盐的德非林:11名患者(79%)的症状完全缓解,2名患者的症状部分缓解:局限性:回顾性队列设计:这是迄今为止关于因对皮革生产过程中使用的重铬酸钾敏感而引起的tefillin皮炎的最大规模研究。改用不含铬酸盐的特菲林后,预后良好。茶具皮炎的发病率可能比以前想象的要高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Potassium dichromate sensitivity presenting as tefillin dermatitis: A retrospective cohort study

Background

Tefillin are a religious article worn by Jewish men during daily prayer. Tefillin dermatitis secondary to potassium dichromate sensitivity is recognised, but data remain sparse.

Objective

To investigate the prevalence and clinical characteristics of tefillin dermatitis.

Methods

Patients who underwent patch testing with the European baseline series in a tertiary dermatology clinic in 2009–2023 and were diagnosed with tefillin dermatitis were identified by file review and their clinical data recorded.

Results

Of 1679 consecutive male patients tested, 25 (1.49%) were diagnosed with tefillin dermatitis, accounting for 15.34% of all potassium-dichromate-positive patients (163/1679). Mean pre-symptomatic duration of tefillin use was 38 ± 16.9 years, and mean follow-up time, 3.1 ± 2.9 years. Patients presented with an eczematous rash on body areas in direct contact with the leather box or straps of the tefillin. An id reaction was noted in 32%, and sensitivity to other leather accessories, in 44%. Fourteen patients (56%) switched to chromate-free tefillin: symptoms resolved completely in 11 (79%) and partially in 2.

Limitations

Retrospective cohort design.

Conclusion

This is the largest study to date of tefillin dermatitis caused by sensitivity to potassium dichromate used in leather production. Prognosis after switching to chromate-free tefillin was good-to-excellent. Tefillin dermatitis may be more prevalent than previously thought.

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来源期刊
ACS Applied Energy Materials
ACS Applied Energy Materials Materials Science-Materials Chemistry
CiteScore
10.30
自引率
6.20%
发文量
1368
期刊介绍: ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.
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