一份有趣的报告称,两种不同种类的粘菌感染了与 COVID-19 相关的粘孢子虫病(CAM)病例。

IF 1.4 4区 医学 Q4 IMMUNOLOGY Indian Journal of Medical Microbiology Pub Date : 2024-07-01 DOI:10.1016/j.ijmmb.2024.100656
Harsimran Kaur , Rimjhim Kanaujia , Gyanaranjan Nayak , Anurag Snehi Ramavat , Sourabha Patro , Anup Ghosh , Arunaloke Chakrabarti , Shivaprakash M. Rudramurthy
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引用次数: 0

摘要

在对COVID-19相关粘孢子菌病(CAM)的调查中,我们发现了五例CAM病例,其中分离出两种不同的粘孢子菌。所有病例均有糖尿病史,临床特征显示为鼻眶粘孢子菌病。患者的鼻腔刮片/活检样本中生长出不同的菌种:Rhizopus arrhizus、R. homothallicus(n=2);R. homothallicus、Lictheimia corymbifera(n=1);R. arrhizus、Mucor spp(n=1);L. corymbifera、Apophysomyces variabilis(n=1)。所有患者都接受了手术和药物(脂质体两性霉素 B)治疗。除一名患者外,其他患者均存活下来。CAM中不止一种粘菌的混合感染是独一无二的,值得进行流行病学调查。
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An interesting report of COVID-19 associated mucormycosis (CAM) cases by two different species of Mucorales

During surge of COVID-19-associated mucormycosis (CAM), we identified five cases of CAM where two different species of Mucorales were isolated. All had history of diabetes mellitus and presented with clinical features suggesting rhino-orbital mucormycosis. The patients grew different species from their nasal scraping/biopsy samples, Rhizopus arrhizus, R. homothallicus (n = 2); R. homothallicus, Lictheimia corymbifera (n = 1); R. arrhizus, Mucor spp (n = 1); and L. corymbifera, Apophysomyces variabilis (n = 1). All patients underwent surgical and medical (liposomal amphotericin B) treatment. All, except one growing A. variabilis and L. corymbifera survived. Mixed infection by more than one Mucorales in CAM is unique and warrants epidemiological investigation.

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期刊介绍: Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.
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