Shuangjin Liu, Zihao Zeng, Qi Qi, Qin Yang, Yiqiu Hu
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引用次数: 0
摘要
研究背景本研究基于基因-环境相互作用范式，探讨了同伴关系对青少年孤独感的影响以及心理复原力和催产素受体基因（OXTR）的作用：方法：对 619 名青少年进行抽样调查，并采集他们的口腔细胞进行 DNA 提取和基因分型：结果表明：（1）同伴关系和心理复原力对青少年孤独感均有显著影响；（2）心理复原力对青少年同伴关系和孤独感之间的关系有部分中介作用；（3）OXTR基因rs53576多态性对中介模型间接路径的前半部分和后半部分均有调节作用。具体而言，rs53576多态性A/A基因型携带者显示同伴关系对青少年心理复原力的影响显著增强，而rs53576多态性G/G基因型携带者显示心理复原力对青少年孤独感的影响显著增强：这些发现有助于从同伴关系、心理复原力和OXTR基因多态性等方面阐明青少年孤独感的发展机制。
The Effect of Peer Relationships on Adolescent Loneliness: The Role of Psychological Resilience and the OXTR Gene.
Background: Based on the gene-environment interaction paradigm, this study explored the effect of peer relationships on adolescent loneliness and the role of psychological resilience and the oxytocin receptor gene (OXTR).
Methods: A survey was conducted in a sample of 619 adolescents, and their oral cells were collected for DNA extraction and genotyping.
Results: The results showed that (1) both peer relationships and psychological resilience significantly affected adolescent loneliness; (2) psychological resilience partially mediated the relationship between peer relationships and loneliness in adolescents; (3) OXTR gene rs53576 polymorphism moderated both the first and second half of the indirect pathway of the mediation model. Specifically, carriers of the rs53576 polymorphism A/A genotype showed a significantly enhanced effect of peer relationships on adolescent psychological resilience, while carriers of the rs53576 polymorphism G/G genotype showed a significantly enhanced effect of psychological resilience on adolescent loneliness.
Conclusion: These findings helped elucidate the developmental mechanisms of adolescent loneliness in terms of peer relationships, psychological resilience, and OXTR gene polymorphisms.
期刊介绍：
Psychology Research and Behavior Management is an international, peer-reviewed, open access journal focusing on the science of psychology and its application in behavior management to develop improved outcomes in the clinical, educational, sports and business arenas. Specific topics covered in the journal include: -Neuroscience, memory and decision making -Behavior modification and management -Clinical applications -Business and sports performance management -Social and developmental studies -Animal studies The journal welcomes submitted papers covering original research, clinical studies, surveys, reviews and evaluations, guidelines, expert opinion and commentary, case reports and extended reports.
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