饮食和生活方式如何微调肠道微生物组,促进健康老龄化。

IF 10.6 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Annual review of food science and technology Pub Date : 2024-06-01 DOI:10.1146/annurev-food-072023-034458
M Tamayo, M Olivares, P Ruas-Madiedo, A Margolles, J C Espín, I Medina, M V Moreno-Arribas, S Canals, C R Mirasso, S Ortín, H Beltrán-Sanchez, A Palloni, F A Tomás-Barberán, Y Sanz
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引用次数: 0

摘要

衰老过程中会发生许多生理、社会和心理变化,从而增加罹患慢性疾病、虚弱和依赖性的风险。这些变化会对肠道微生物群产生不利影响,这种现象被称为微生物老化。这些微生物群的变化反过来又与老年相关疾病的发生有关。肠道微生物群对生活方式和饮食习惯的改变反应灵敏,显示出灵活性,这也为促进健康老龄化提供了可操作的工具。本综述首先介绍了在健康或不健康老龄化过程中改变肠道微生物群组成和功能的主要生活方式和社会经济因素,其次介绍了在定义和促进健康老龄化方面取得的进展,包括微生物信息人工智能工具、个性化饮食模式和食品益生菌系统。
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How Diet and Lifestyle Can Fine-Tune Gut Microbiomes for Healthy Aging.

Many physical, social, and psychological changes occur during aging that raise the risk of developing chronic diseases, frailty, and dependency. These changes adversely affect the gut microbiota, a phenomenon known as microbe-aging. Those microbiota alterations are, in turn, associated with the development of age-related diseases. The gut microbiota is highly responsive to lifestyle and dietary changes, displaying a flexibility that also provides anactionable tool by which healthy aging can be promoted. This review covers, firstly, the main lifestyle and socioeconomic factors that modify the gut microbiota composition and function during healthy or unhealthy aging and, secondly, the advances being made in defining and promoting healthy aging, including microbiome-informed artificial intelligence tools, personalized dietary patterns, and food probiotic systems.

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来源期刊
CiteScore
22.40
自引率
0.80%
发文量
20
审稿时长
>12 weeks
期刊介绍: Since 2010, the Annual Review of Food Science and Technology has been a key source for current developments in the multidisciplinary field. The covered topics span food microbiology, food-borne pathogens, and fermentation; food engineering, chemistry, biochemistry, rheology, and sensory properties; novel ingredients and nutrigenomics; emerging technologies in food processing and preservation; and applications of biotechnology and nanomaterials in food systems.
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