通过生物胶原蛋白和富血小板纤维蛋白对 Seibert I 类后嵴缺陷进行简化 GBR 治疗和评估:回顾性研究。

IF 4.4 4区 医学 Q2 CELL & TISSUE ENGINEERING Tissue engineering and regenerative medicine Pub Date : 2024-08-01 Epub Date: 2024-06-28 DOI:10.1007/s13770-024-00654-0
Zhi Wang, Yafeng Zheng, Jiaqi Xu, Qi Jia, Heng Bo Jiang, Eui-Seok Lee
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引用次数: 0

摘要

背景:经典的引导骨再生(GBR)治疗可为牙脊缺损带来良好的临床效果。然而,对于轻微的牙脊缺损,没有必要在后部非美学区域进行广泛的骨增量。方法:22 例 Seibert I 类牙脊骨缺损采用 BC 治疗并覆盖 PRF 膜(简化的引导骨再生,简化的 GBR),另外 22 例采用 Bio-Oss 治疗并覆盖 Bio-Gide(经典的 GBR)。术后 6 个月进行锥形束计算机断层扫描,比较牙脊的水平宽度(HW)和颊嵴的水平宽度,以评估成骨效果。此外,还对颊嵴轮廓形态进行了研究和分类:结果:简化 GBR 的颊嵴轮廓 14 例为 A 型,7 例为 B 型,1 例为 C 型;经典 GBR 的颊嵴轮廓 11 例为 A 型,8 例为 B 型,3 例为 C 型。简化 GBR 治疗的平均 HW 明显增加了 1.50 mm,而传统 GBR 治疗的平均 HW 增加了 1.83 mm:结论:联合使用 BC 和 PRF 对骨增量有显著效果,这种治疗方法在矫正 Seibert I 类后牙脊缺损方面具有良好的临床效果。本研究中对重建效果的形态学分类可用于今后的临床工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A Simplified GBR Treatment and Evaluation of Posterior Seibert Class I Ridge Defects via Bio-collagen and Platelet-Rich Fibrin: A Retrospective Study.

Background: Classical guided bone regeneration (GBR) treatments can achieve favorable clinical results for ridge defects. However, extensive bone augmentation in the non-esthetic area in the posterior region for minor ridge defects is unnecessary. Therefore, this study used a collagen and Platelet-rich fibrin (PRF) mixture for bone augmentation on minor posterior ridge defects and evaluated the effects.

Methods: 22 Seibert Class I ridge defects were treated with BC and covered with a PRF membrane (simplified guided bone regeneration, simplified GBR) and other 22 were treated with Bio-Oss and covered with Bio-Gide (classical GBR). Cone-beam computed tomography imaging was conducted 6 months post-surgery to compare the ridge's horizontal width (HW) and buccal ridge's horizontal width to assess the osteogenic effect. In addition, the buccal ridge contour morphology was studied and classified.

Results: The buccal ridge contour of simplified GBR was Type A in 14 cases, Type B in 7 cases, and Type C in 1 case and it of classical GBR was Type A in 11 cases, Type B in 8 cases, and Type C in 3 cases. The mean HW significantly increased by 1.50 mm of simplified GBR treatment, while it increased by 1.83 mm in classical GBR treatment.

Conclusion: The combined use of BC and PRF had a significant effect on bone augmentation and this treatment exhibited promising clinical results for correcting posterior Seibert Class I ridge defects. The morphological classification of the reconstructive effect in this study can be utilized in future clinical work.

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来源期刊
Tissue engineering and regenerative medicine
Tissue engineering and regenerative medicine CELL & TISSUE ENGINEERING-ENGINEERING, BIOMEDICAL
CiteScore
6.80
自引率
5.60%
发文量
83
审稿时长
6-12 weeks
期刊介绍: Tissue Engineering and Regenerative Medicine (Tissue Eng Regen Med, TERM), the official journal of the Korean Tissue Engineering and Regenerative Medicine Society, is a publication dedicated to providing research- based solutions to issues related to human diseases. This journal publishes articles that report substantial information and original findings on tissue engineering, medical biomaterials, cells therapy, stem cell biology and regenerative medicine.
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