利用深度强化学习方法对 COVID-19 疾病进行建模和控制。

IF 2.6 4区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Medical & Biological Engineering & Computing Pub Date : 2024-12-01 Epub Date: 2024-06-28 DOI:10.1007/s11517-024-03153-5
Nazanin Ghazizadeh, Sajjad Taghvaei, Seyyed Arash Haghpanah
{"title":"利用深度强化学习方法对 COVID-19 疾病进行建模和控制。","authors":"Nazanin Ghazizadeh, Sajjad Taghvaei, Seyyed Arash Haghpanah","doi":"10.1007/s11517-024-03153-5","DOIUrl":null,"url":null,"abstract":"<p><p>The prevalence of epidemics has been studied by researchers in various fields. In the last 2 years, the outbreak of COVID-19 has affected the health, economy, and industry of communities around the world and has caused the death of millions of people. Therefore, many researchers have tried to model and control the prevalence of this disease. In this article, the new SQEIAR model for the spread of the COVID-19 disease is provided, which, compared to previous models, explores the effects of additional interventions on the outbreak and incorporates a wider range of variables and parameters to enhance its accuracy and alignment with reality. These modifications in the model lead to a more rapid eradication and control of the disease. This model includes six variables of the group of susceptible, quarantined, exposed, symptomatic, asymptomatic, and recovered individuals and includes three control inputs such as quarantine of susceptible, vaccination, and treatments. In order to minimize symptomatic infectious individuals and susceptible individuals and also to reduce treatment, vaccination, and quarantine costs, an optimal control approach using the Deep Deterministic Policy Gradient (DDPG) method has been applied to the system. This algorithm is applied to the model in different cases of control inputs, and for each case, optimal control inputs are obtained. In the following, the number of deaths due to the disease and the total number of symptomatic infectious individuals for each of these optimal control cases has been calculated. The results of the implemented control structure demonstrated a reduction of 60% in the number of deaths and 74% in the number of symptomatically infected individuals compared to the uncontrolled model. Finally, to test the performance of the control system, noise was applied to the system in various ways, including three methods: applying noise to observer variables, applying noise to control inputs, and applying uncertainty to model parameters. Therefore, we found that this control system was robust and performed well in different conditions despite the disturbance.</p>","PeriodicalId":49840,"journal":{"name":"Medical & Biological Engineering & Computing","volume":" ","pages":"3653-3670"},"PeriodicalIF":2.6000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modeling and control of COVID-19 disease using deep reinforcement learning method.\",\"authors\":\"Nazanin Ghazizadeh, Sajjad Taghvaei, Seyyed Arash Haghpanah\",\"doi\":\"10.1007/s11517-024-03153-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The prevalence of epidemics has been studied by researchers in various fields. In the last 2 years, the outbreak of COVID-19 has affected the health, economy, and industry of communities around the world and has caused the death of millions of people. Therefore, many researchers have tried to model and control the prevalence of this disease. In this article, the new SQEIAR model for the spread of the COVID-19 disease is provided, which, compared to previous models, explores the effects of additional interventions on the outbreak and incorporates a wider range of variables and parameters to enhance its accuracy and alignment with reality. These modifications in the model lead to a more rapid eradication and control of the disease. This model includes six variables of the group of susceptible, quarantined, exposed, symptomatic, asymptomatic, and recovered individuals and includes three control inputs such as quarantine of susceptible, vaccination, and treatments. In order to minimize symptomatic infectious individuals and susceptible individuals and also to reduce treatment, vaccination, and quarantine costs, an optimal control approach using the Deep Deterministic Policy Gradient (DDPG) method has been applied to the system. This algorithm is applied to the model in different cases of control inputs, and for each case, optimal control inputs are obtained. In the following, the number of deaths due to the disease and the total number of symptomatic infectious individuals for each of these optimal control cases has been calculated. The results of the implemented control structure demonstrated a reduction of 60% in the number of deaths and 74% in the number of symptomatically infected individuals compared to the uncontrolled model. Finally, to test the performance of the control system, noise was applied to the system in various ways, including three methods: applying noise to observer variables, applying noise to control inputs, and applying uncertainty to model parameters. Therefore, we found that this control system was robust and performed well in different conditions despite the disturbance.</p>\",\"PeriodicalId\":49840,\"journal\":{\"name\":\"Medical & Biological Engineering & Computing\",\"volume\":\" \",\"pages\":\"3653-3670\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical & Biological Engineering & Computing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s11517-024-03153-5\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical & Biological Engineering & Computing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s11517-024-03153-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/28 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0

摘要

各领域的研究人员一直在研究流行病的流行情况。在过去两年中,COVID-19 的爆发影响了世界各地社区的健康、经济和工业,并造成数百万人死亡。因此,许多研究人员试图模拟和控制这种疾病的流行。本文提供了 COVID-19 疾病传播的新 SQEIAR 模型,与以前的模型相比,该模型探讨了额外干预措施对疾病爆发的影响,并纳入了更广泛的变量和参数,以提高其准确性和与现实的一致性。对模型的这些修改可更快地根除和控制疫情。该模型包括易感人群、隔离人群、暴露人群、有症状人群、无症状人群和康复人群六个变量,并包括易感人群隔离、疫苗接种和治疗等三个控制输入。为了最大限度地减少无症状感染者和易感人群,同时降低治疗、疫苗接种和检疫成本,该系统采用了深度确定性策略梯度法(DDPG)的最优控制方法。该算法适用于不同控制输入情况下的模型,并在每种情况下获得最佳控制输入。随后,计算了每种最佳控制情况下的疾病死亡人数和有症状的感染者总数。实施控制结构的结果表明,与不受控制的模型相比,死亡人数减少了 60%,有症状的感染者人数减少了 74%。最后,为了测试控制系统的性能,我们以不同的方式对系统施加了噪声,包括三种方法:对观测变量施加噪声、对控制输入施加噪声以及对模型参数施加不确定性。因此,我们发现该控制系统具有鲁棒性,在不同条件下均表现良好,尽管存在干扰。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Modeling and control of COVID-19 disease using deep reinforcement learning method.

The prevalence of epidemics has been studied by researchers in various fields. In the last 2 years, the outbreak of COVID-19 has affected the health, economy, and industry of communities around the world and has caused the death of millions of people. Therefore, many researchers have tried to model and control the prevalence of this disease. In this article, the new SQEIAR model for the spread of the COVID-19 disease is provided, which, compared to previous models, explores the effects of additional interventions on the outbreak and incorporates a wider range of variables and parameters to enhance its accuracy and alignment with reality. These modifications in the model lead to a more rapid eradication and control of the disease. This model includes six variables of the group of susceptible, quarantined, exposed, symptomatic, asymptomatic, and recovered individuals and includes three control inputs such as quarantine of susceptible, vaccination, and treatments. In order to minimize symptomatic infectious individuals and susceptible individuals and also to reduce treatment, vaccination, and quarantine costs, an optimal control approach using the Deep Deterministic Policy Gradient (DDPG) method has been applied to the system. This algorithm is applied to the model in different cases of control inputs, and for each case, optimal control inputs are obtained. In the following, the number of deaths due to the disease and the total number of symptomatic infectious individuals for each of these optimal control cases has been calculated. The results of the implemented control structure demonstrated a reduction of 60% in the number of deaths and 74% in the number of symptomatically infected individuals compared to the uncontrolled model. Finally, to test the performance of the control system, noise was applied to the system in various ways, including three methods: applying noise to observer variables, applying noise to control inputs, and applying uncertainty to model parameters. Therefore, we found that this control system was robust and performed well in different conditions despite the disturbance.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Medical & Biological Engineering & Computing
Medical & Biological Engineering & Computing 医学-工程:生物医学
CiteScore
6.00
自引率
3.10%
发文量
249
审稿时长
3.5 months
期刊介绍: Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE).
期刊最新文献
Multi-file dynamic compression method based on classification algorithm in DNA storage. Continuous mobile measurement of camptocormia angle using four accelerometers. Modeling and control of COVID-19 disease using deep reinforcement learning method. Left ventricle diastolic vortex ring characterization in ischemic cardiomyopathy: insight into atrio-ventricular interplay. DNN-BP: a novel framework for cuffless blood pressure measurement from optimal PPG features using deep learning model.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1