{"title":"用于分辨食品中多种硫化物的 Cu2(OH)3NO3 纳米酶传感器阵列。","authors":"Wenjie Jing, Yu Wang, Qihao Shi, Yajun Yang, Yujie Dai, Fufeng Liu","doi":"10.1016/j.bios.2024.116529","DOIUrl":null,"url":null,"abstract":"<div><p>In the food industry, sulfides are commonly used as preservatives and flavor regulators. However, long-term excessive intake of sulfides can lead to serious health problems. Therefore, developing efficient sulfide detection methods is particularly important. Here, we have effectively synthesized a novel bifunctional copper hydroxide nitrate (Cu<sub>2</sub>(OH)<sub>3</sub>NO<sub>3</sub>) nanozyme with outstanding peroxidase-like and laccase-like behaviors in basic deep eutectic solvents (DES). Because the various types of sulfides have diverse regulatory effects on the two catalytic behaviors of Cu<sub>2</sub>(OH)<sub>3</sub>NO<sub>3</sub>, a two channel nanozyme sensor array based on the peroxidase-like and laccase-like behaviors of Cu<sub>2</sub>(OH)<sub>3</sub>NO<sub>3</sub> was constructed and successfully used for the identification of six kinds of sulfides (Na<sub>2</sub>S, Na<sub>2</sub>S<sub>2</sub>O<sub>3</sub>, Na<sub>2</sub>SO<sub>3</sub>, Na<sub>2</sub>SO<sub>4</sub>, NaHSO<sub>3</sub>, and Na<sub>2</sub>S<sub>2</sub>O<sub>8</sub>). Remarkably, the sensor array has achieved successful discrimination among six sulfides present in wine, egg, and milk samples. Finally, the sensor array has successfully distinguished and differentiated three actual samples (wine, egg, and milk). This study is of great significance in promoting the efficient construction of array units and improving the effective identification of sulfides in complex food samples.</p></div>","PeriodicalId":259,"journal":{"name":"Biosensors and Bioelectronics","volume":null,"pages":null},"PeriodicalIF":10.7000,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cu2(OH)3NO3 nanozyme sensor array for the discrimination of multiple sulfides in food\",\"authors\":\"Wenjie Jing, Yu Wang, Qihao Shi, Yajun Yang, Yujie Dai, Fufeng Liu\",\"doi\":\"10.1016/j.bios.2024.116529\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In the food industry, sulfides are commonly used as preservatives and flavor regulators. However, long-term excessive intake of sulfides can lead to serious health problems. Therefore, developing efficient sulfide detection methods is particularly important. Here, we have effectively synthesized a novel bifunctional copper hydroxide nitrate (Cu<sub>2</sub>(OH)<sub>3</sub>NO<sub>3</sub>) nanozyme with outstanding peroxidase-like and laccase-like behaviors in basic deep eutectic solvents (DES). Because the various types of sulfides have diverse regulatory effects on the two catalytic behaviors of Cu<sub>2</sub>(OH)<sub>3</sub>NO<sub>3</sub>, a two channel nanozyme sensor array based on the peroxidase-like and laccase-like behaviors of Cu<sub>2</sub>(OH)<sub>3</sub>NO<sub>3</sub> was constructed and successfully used for the identification of six kinds of sulfides (Na<sub>2</sub>S, Na<sub>2</sub>S<sub>2</sub>O<sub>3</sub>, Na<sub>2</sub>SO<sub>3</sub>, Na<sub>2</sub>SO<sub>4</sub>, NaHSO<sub>3</sub>, and Na<sub>2</sub>S<sub>2</sub>O<sub>8</sub>). Remarkably, the sensor array has achieved successful discrimination among six sulfides present in wine, egg, and milk samples. Finally, the sensor array has successfully distinguished and differentiated three actual samples (wine, egg, and milk). This study is of great significance in promoting the efficient construction of array units and improving the effective identification of sulfides in complex food samples.</p></div>\",\"PeriodicalId\":259,\"journal\":{\"name\":\"Biosensors and Bioelectronics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":10.7000,\"publicationDate\":\"2024-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biosensors and Bioelectronics\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0956566324005347\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors and Bioelectronics","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0956566324005347","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOPHYSICS","Score":null,"Total":0}
Cu2(OH)3NO3 nanozyme sensor array for the discrimination of multiple sulfides in food
In the food industry, sulfides are commonly used as preservatives and flavor regulators. However, long-term excessive intake of sulfides can lead to serious health problems. Therefore, developing efficient sulfide detection methods is particularly important. Here, we have effectively synthesized a novel bifunctional copper hydroxide nitrate (Cu2(OH)3NO3) nanozyme with outstanding peroxidase-like and laccase-like behaviors in basic deep eutectic solvents (DES). Because the various types of sulfides have diverse regulatory effects on the two catalytic behaviors of Cu2(OH)3NO3, a two channel nanozyme sensor array based on the peroxidase-like and laccase-like behaviors of Cu2(OH)3NO3 was constructed and successfully used for the identification of six kinds of sulfides (Na2S, Na2S2O3, Na2SO3, Na2SO4, NaHSO3, and Na2S2O8). Remarkably, the sensor array has achieved successful discrimination among six sulfides present in wine, egg, and milk samples. Finally, the sensor array has successfully distinguished and differentiated three actual samples (wine, egg, and milk). This study is of great significance in promoting the efficient construction of array units and improving the effective identification of sulfides in complex food samples.
期刊介绍:
Biosensors & Bioelectronics, along with its open access companion journal Biosensors & Bioelectronics: X, is the leading international publication in the field of biosensors and bioelectronics. It covers research, design, development, and application of biosensors, which are analytical devices incorporating biological materials with physicochemical transducers. These devices, including sensors, DNA chips, electronic noses, and lab-on-a-chip, produce digital signals proportional to specific analytes. Examples include immunosensors and enzyme-based biosensors, applied in various fields such as medicine, environmental monitoring, and food industry. The journal also focuses on molecular and supramolecular structures for enhancing device performance.