非危重病人的胰岛素起始方案:对美国 32 家学术医院的调查。

IF 5.7 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes technology & therapeutics Pub Date : 2024-07-15 DOI:10.1089/dia.2024.0120
Hou-Hsien Chiang, Steven E Kahn, Irl B Hirsch
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引用次数: 0

摘要

入院后立即控制血糖非常困难。内分泌学会的指南建议按计划开始胰岛素治疗,剂量为 0.2-0.5 单位/公斤/天,但目前还没有严格的研究支持这一建议。为了了解当前实践的变异性,我们调查了美国一流学术医院对非危重病人的胰岛素起始算法。在报告了算法的 20 家医院中,12 家医院规定了哪些患者应从基础/营养胰岛素开始,而 5 家医院规定了哪些患者应从修正胰岛素开始。在估算初始胰岛素需求量时,使用了基于体重和/或基于家庭剂量的计算方法,并使用了不同的修饰符。此外,在选择校正剂量算法时还考虑了各种因素。总之,在美国的学术医院中,非危重病人入院时胰岛素剂量的确定方法存在差异。这种不一致性表明,今后需要对初始胰岛素需求量进行估算。
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Starting Insulin Algorithms for Noncritical Illness: A Survey of 32 Academic Hospitals in the United States.

Glycemic control immediately upon hospitalization is difficult. Endocrine Society guidelines suggest starting scheduled insulin therapy at 0.2-0.5 units/kg/day, but there has been no rigorous study to support this recommendation. To understand the variability of current practice, we surveyed starting insulin algorithms for noncritically ill patients among the top-ranking academic hospitals in the United States. Among the 20 hospitals with reported algorithms, 12 specified which patients should start with basal/nutritional insulin, whereas 5 specified who should start with only correction insulin. Weight-based and/or home-dose-based calculations were used to estimate the initial insulin requirements with various modifiers. In addition, various factors were considered when choosing among the correction dose algorithms. In summary, among the U.S. academic hospitals, there is variability in methods for determining insulin dosing on admission for noncritically ill patients. This inconsistency suggests that future studies to estimate initial insulin requirements are required.

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来源期刊
Diabetes technology & therapeutics
Diabetes technology & therapeutics 医学-内分泌学与代谢
CiteScore
10.60
自引率
14.80%
发文量
145
审稿时长
3-8 weeks
期刊介绍: Diabetes Technology & Therapeutics is the only peer-reviewed journal providing healthcare professionals with information on new devices, drugs, drug delivery systems, and software for managing patients with diabetes. This leading international journal delivers practical information and comprehensive coverage of cutting-edge technologies and therapeutics in the field, and each issue highlights new pharmacological and device developments to optimize patient care.
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