用于放射治疗的数据驱动门控正电子发射断层扫描/计算机断层扫描技术

Tinsu Pan , Dershan Luo
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引用次数: 0

摘要

目的基于软件的数据驱动门控(DDG)正电子发射断层扫描/计算机断层扫描(PET/CT)已经取代了基于硬件的4D PET/CT。本文的目的是对 DDG PET/CT 进行综述,该技术可提高放疗(RT)中全身(WB)PET/CT 治疗反应评估、肿瘤运动评估和靶肿瘤轮廓绘制的准确性。材料和方法本综述基于系统性文献综述,涵盖了硬件选通的 4D PET/CT、PET 仪器的进步、DDG PET、DDG CT 和 DDG PET/CT 等主题。其中包括对大轴向视场(AFOV)PET 探测器的讨论,以及对 DDG PET 和 DDG PET/CT 临床结果的回顾。DDG CT 与需要硬件选通的 4D CT 相比,与 DDG PET 更为兼容。DDG CT可取代4D CT进行RT检查。结论DDG PET/CT可以纠正WB PET/CT中的错误配准和肿瘤运动伪影,并为RT提供配准PET/CT的定量PET和肿瘤运动信息。
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Data-driven gated positron emission tomography/computed tomography for radiotherapy

Purpose

Software-based data-driven gated (DDG) positron emission tomography/computed tomography (PET/CT) has replaced hardware-based 4D PET/CT. The purpose of this article was to review DDG PET/CT, which could improve the accuracy of treatment response assessment, tumor motion evaluation, and target tumor contouring with whole-body (WB) PET/CT for radiotherapy (RT).

Material and methods

This review covered the topics of 4D PET/CT with hardware gating, advancements in PET instrumentation, DDG PET, DDG CT, and DDG PET/CT based on a systematic literature review. It included a discussion of the large axial field-of-view (AFOV) PET detector and a review of the clinical results of DDG PET and DDG PET/CT.

Results

DDG PET matched or outperformed 4D PET with hardware gating. DDG CT was more compatible with DDG PET than 4D CT, which required hardware gating. DDG CT could replace 4D CT for RT. DDG PET and DDG CT for DDG PET/CT can be incorporated in a WB PET/CT of less than 15 min scan time on a PET/CT scanner of at least 25 cm AFOV PET detector.

Conclusions

DDG PET/CT could correct the misregistration and tumor motion artifacts in a WB PET/CT and provide the quantitative PET and tumor motion information of a registered PET/CT for RT.

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来源期刊
Physics and Imaging in Radiation Oncology
Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation
CiteScore
5.30
自引率
18.90%
发文量
93
审稿时长
6 weeks
期刊最新文献
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