3D 打印通气管及其对生物模型的影响。

IF 3.2 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 3D printing in medicine Pub Date : 2024-07-02 DOI:10.1186/s41205-024-00225-y
Luis Humberto Govea-Camacho, Irma Yolanda Castillo-López, Sergio Alejandro Carbajal-Castillo, Alejandro Gonzalez-Ojeda, Gabino Cervantes-Guevara, Enrique Cervantes-Pérez, Sol Ramírez-Ochoa, Sergio Jiram Vázquez-Sánchez, Gonzalo Delgado-Hernández, Jaime Alberto Tavares-Ortega, Samantha Emily González-Muñoz, Clotilde Fuentes-Orozco
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引用次数: 0

摘要

背景:急性中耳炎(AOM)会导致炎症和听力损失。通气管是治疗的关键。3D打印技术可提高耳鼻喉科假体的精度和适应性:2020 年 7 月至 12 月,对 Wistar 大鼠进行了实验研究。设计了三维鼓室造口管模型,并在廉价的三维打印机上进行了技术规格和测试。鼓室造口管通过内窥镜插入:对 5 只双耳植入鼓膜的大鼠进行了手术。结果:对五只双耳植入鼓膜的大鼠进行了手术,发现了干预前的病变,如鼓膜后缩和胶耳。聚乳酸印制鼓室造口管经调整后情况有所改善。组织病理学结果显示中耳和内耳损伤严重:在我们的研究中,设计和三维打印的植入物在修改后能实现预期功能,高度为 5 毫米。并发症包括聚乳酸降解和耳损伤。在观察期间没有发生任何不良事件,因此有必要对三维打印植入物进行进一步研究。
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3D printed ventilation tubes and their effect on biological models.

Background: Acute otitis media (AOM) causes inflammation and hearing loss. Ventilation tubes are key in treatment. 3D printing improves prostheses in otorhinolaryngology, offering precision and greater adaptability.

Materials and methods: An experimental study was conducted with Wistar rats from July to December 2020. 3D tympanostomy tube models were designed, with technical specifications and tests performed on inexpensive 3D printers. The tympanostomy tube was inserted endoscopically.

Results: Procedures were performed on five rats with implants in both ears. Pre-intervention pathologies, such as atical retraction and glue ear, were found. The PLA-printed tympanostomy tube showed improvement after adjustments. Histopathological results revealed significant middle and inner ear damage.

Conclusion: In our study, the design and 3D printing of implants fulfilled the desired functions when modified, with a height of 5 mm. Complications included PLA degradation and ear damage. There were no adverse events during observation, highlighting the need for further research on 3D-printed implants.

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