D Pérez Fentes, P Willisch, S Martínez Breijoo, M Domínguez, U Anido, C Álvarez, A Gómez Caamaño
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引用次数: 0
摘要
近年来,前列腺癌(PC)治疗的各个方面都发生了重大变化,包括实施治疗策略,如使用阿比特龙、阿帕鲁胺、恩扎鲁胺或达罗鲁胺等新型激素药物,以及采用新一代成像技术(NGI)。然而,有关 NGI 的作用以及根据其结果做出治疗决策的证据并不充分。按照晚期前列腺癌共识会议(APCCC)的方法,多学科专家达成了一项共识,以解决与 NGI 的使用和四种重点情况下的临床管理有关的争议问题:局部 PC、根治性前列腺切除术后 PC、根治性放疗后 PC 和转移性激素敏感 PC。该共识代表了肿瘤内科、肿瘤放射科和泌尿科医生的观点,为临床实践提供了有用的建议。
Controversies in prostate cancer management: Consensus recommendations from experts in northern Spain.
In recent years, various aspects of prostate cancer (PC) management have undergone significant changes, including the implementation of therapeutic strategies such as the use of new hormonal agents like abiraterone, apalutamide, enzalutamide or darolutamide and the incorporation of next generation imaging techniques (NGI). However, the evidence regarding the role of NGI and the therapeutic decision-making based on their findings is not solid. Following the methodology of the Advanced Prostate Cancer Consensus Conference (APCCC), a multidisciplinary expert consensus was developed to address controversial questions concerning the use of NGI and clinical management in four priority scenarios: localized PC, PC after radical prostatectomy, PC after radiotherapy with curative intent, and metastatic hormone-sensitive PC. This consensus represents the opinions of medical oncology, radiation oncology and urology physicians and provides useful recommendations for clinical practice.