炎症性肠病的 PET：FAPI 新时代？

IF 2.3 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical and Translational Imaging Pub Date : 2024-06-25 DOI:10.1007/s40336-024-00649-w

F. Galiandro, F. Scaldaferri, L. Sofo, M.R. Ruggiero, D.A. Pizzuto, L. Laterza, V. Tondolo, S. Annunziata

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引用次数: 0

摘要

目的评估实验性 FAPI PET/CT 在炎症性肠病中的作用。方法在科学文献中检索有关 FAPI PET/CT 在炎症性肠病中作用的首批临床论文，并与传统的临床和放射学检查（如 CT、MRI 和 18F-FDG PET/CT）进行比较，在本短篇综述中进行评论。结果到目前为止，关于实验性 FAPI PET/CT 在炎症性肠病中的作用的首次人体试验只发表了几篇，显示了有趣的准确性数据，并可能对克罗恩病患者的临床管理产生影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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PET in inflammatory bowel diseases: a new FAPI era?

Purpose

To evaluate the role of experimental FAPI PET/CT in inflammatory bowel diseases.

Methods

First clinical papers about FAPI PET/CT in inflammatory bowel diseases were retrieved in scientific literature and commented in this short review, compared with conventional clinical and radiological examinations (e.g. CT, MRI and ¹⁸F-FDG PET/CT).

Results

Only few first-in-human trials have been published until now about the role of experimental FAPI PET/CT in inflammatory bowel diseases, showing interesting accuracy data and possible impact on clinical management in patients with Crohn’s disease.

Conclusion

Larger studies are needed to confirm and expand the role of this diagnostic tool in clinics.

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来源期刊

Clinical and Translational Imaging Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

3.60

自引率

4.80%

发文量

期刊介绍： Clinical and Translational Imaging is an international journal that publishes timely, up-to-date summaries on clinical practice and translational research and clinical applications of approved and experimental radiopharmaceuticals for diagnostic and therapeutic purposes. Coverage includes such topics as advanced preclinical evidence in the fields of physics, dosimetry, radiation biology and radiopharmacy with relevance to applications in human subjects. The journal benefits a readership of nuclear medicine practitioners and allied professionals involved in molecular imaging and therapy.