融合噻吩并吡啶合成及其治疗应用的最新进展

Ranjay Shaw , Ritu Tewari , Monika Yadav , Ekta Pandey , Khyati Tripathi , Jyoti Rani , Ismail Althagafi , Ramendra Pratap
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引用次数: 0

摘要

融合噻吩并吡啶是一类杂环分子,因其独特的结构特征和多变的化学性质而受到越来越多的关注。本综述系统研究了制备融合噻吩并吡啶衍生物的最新合成方法,强调了有助于实现结构多样性的创新方法。此外,还讨论了融合噻吩并吡啶在治疗方面的广泛应用,包括它们在不同疾病中的用途。综述探讨了融合噻吩并吡啶的药理活性和生物特性,揭示了它们在药物发现和开发中的作用。通过全面概述融合噻吩并吡啶的化学合成和治疗应用方面的最新进展,这篇综述将成为不断发展的药物化学领域研究人员和从业人员的宝贵资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Recent advancements in the synthesis of fused thienopyridines and their therapeutic applications

Fused thienopyridines represent a class of heterocyclic molecules that have garnered increasing attention due to their unique structural features and versatile chemical properties. This review systematically examines the latest synthetic methodologies employed in preparing fused thienopyridine derivatives, emphasizing innovative approaches that contribute to structural diversity. Moreover, the discussion extends to the broad spectrum of therapeutic applications that fused thienopyridines offer, encompassing their utility in different diseases. The review explores the pharmacological activities and biological properties of fused thienopyridines, shedding light on their role in drug discovery and development. By offering a comprehensive overview of recent advancements in both the chemical synthesis and therapeutic applications of fused thienopyridines, this review will serve as a valuable resource for researchers and practitioners navigating the evolving landscape of medicinal chemistry.

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