{"title":"糠秕马拉色菌血流感染：仍是临床实践中的诊断难题","authors":"Rosalba Petruccelli , Terenzio Cosio , Valeria Camicia , Carlotta Fiorilla , Roberta Gaziano , Cartesio D'Agostini","doi":"10.1016/j.mmcr.2024.100657","DOIUrl":null,"url":null,"abstract":"<div><p>The opportunistic fungus <em>Malassezia furfur</em> (<em>M. furfur</em>) can cause either cutaneous or systemic infections. We report a case of <em>M. furfur</em> fungemia in a 22-year-old male with T-cell Acute Lymphoblastic Leukemia (T-ALL) who developed concomitant <em>Bacillus cereus</em> (<em>B. cereus</em>) septicemia. The fungal infection was diagnosed by microscopic examination and culture-based methods, while automated blood culture systems and molecular approaches failed in identifying the fungus. Despite appropriate therapy, the patient died 18 days after the hospitalization.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100657"},"PeriodicalIF":1.6000,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000319/pdfft?md5=597966c6ac43ef2d4fda19572fb715eb&pid=1-s2.0-S2211753924000319-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Malassezia furfur bloodstream infection: still a diagnostic challenge in clinical practice\",\"authors\":\"Rosalba Petruccelli , Terenzio Cosio , Valeria Camicia , Carlotta Fiorilla , Roberta Gaziano , Cartesio D'Agostini\",\"doi\":\"10.1016/j.mmcr.2024.100657\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The opportunistic fungus <em>Malassezia furfur</em> (<em>M. furfur</em>) can cause either cutaneous or systemic infections. We report a case of <em>M. furfur</em> fungemia in a 22-year-old male with T-cell Acute Lymphoblastic Leukemia (T-ALL) who developed concomitant <em>Bacillus cereus</em> (<em>B. cereus</em>) septicemia. The fungal infection was diagnosed by microscopic examination and culture-based methods, while automated blood culture systems and molecular approaches failed in identifying the fungus. Despite appropriate therapy, the patient died 18 days after the hospitalization.</p></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"45 \",\"pages\":\"Article 100657\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2211753924000319/pdfft?md5=597966c6ac43ef2d4fda19572fb715eb&pid=1-s2.0-S2211753924000319-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211753924000319\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753924000319","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
摘要
糠秕马拉色菌（M. furfur）可引起皮肤或全身感染。我们报告了一例患有 T 细胞急性淋巴细胞白血病（T-ALL）的 22 岁男性秕糠马拉色菌真菌感染病例，该患者同时患有蜡样芽孢杆菌（B. cereus）败血症。真菌感染是通过显微镜检查和培养方法确诊的，而自动血液培养系统和分子方法均未能鉴定出真菌。尽管进行了适当的治疗，但患者在住院 18 天后死亡。
Malassezia furfur bloodstream infection: still a diagnostic challenge in clinical practice
The opportunistic fungus Malassezia furfur (M. furfur) can cause either cutaneous or systemic infections. We report a case of M. furfur fungemia in a 22-year-old male with T-cell Acute Lymphoblastic Leukemia (T-ALL) who developed concomitant Bacillus cereus (B. cereus) septicemia. The fungal infection was diagnosed by microscopic examination and culture-based methods, while automated blood culture systems and molecular approaches failed in identifying the fungus. Despite appropriate therapy, the patient died 18 days after the hospitalization.
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