利用杂环作为方便的迈克尔供体进行迈克尔加成反应的最新进展

IF 2.8 4区化学 Q1 CHEMISTRY, ORGANIC Asian Journal of Organic Chemistry Pub Date : 2024-10-01 DOI:10.1002/ajoc.202400193

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引用次数: 0

摘要

迈克尔加成反应是当代有机合成的基石，由于它能够形成复杂的碳-碳键和碳-异原子键，因此再次引起了人们的兴趣。在过去几年中，杂环化合物因其结构的多样性和独特的反应活性，无论是否存在碱/过渡金属/有机催化剂，都被严格用作迈克尔供体。本综述囊括了以杂环化合物为迈克尔供体进行迈克尔加成反应的最新化学突破。它全面介绍了 2017 年以来由强效杂环引发的迈克尔加成反应的最新进展，重点介绍了新颖和创新的方法，并提出了战略性见解。

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Current Developments in Michael Addition Reaction using Heterocycles as Convenient Michael Donors

The Michael addition reaction, a cornerstone of contemporary organic synthesis, has witnessed a resurgence of interest owing to its ability to forge intricate carbon‐carbon and carbon‐heteroatom bonds. In the past few years, heterocyclic compounds have been rigorously used as Michael donors, owing to their architectural diversity and distinct reactivity with or without the presence of base/transition metals/organocatalysts. This review encapsulates the latest breakthroughs in chemistry involving Michael addition reaction using heterocyclic compounds as Michael donors. It delivers a comprehensive update on developments in Michael addition reaction triggered by potent heterocycles since 2017, highlighting novel and innovative methodologies, with strategic insights.

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.