将姿势稳定性作为衡量感染和未感染艾滋病毒的老年人跌倒风险的标准。

IF 1.5 4区 医学 Q4 IMMUNOLOGY AIDS research and human retroviruses Pub Date : 2024-07-19 DOI:10.1089/AID.2024.0046
Mary Clare Masters, Laura M Campbell, Jimmy Yu, Anne Heaton, Kristine M Erlandson, Hari Garudadri, Truong Nguyen, David J Moore, Raeanne C Moore
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引用次数: 0

摘要

导言:随着感染艾滋病病毒的老年人(PWH)数量的增加,意外跌倒及其相关的负面健康后果日益受到关注。跌倒风险可通过新型筛查工具进行测量,如使用力板技术评估姿势稳定性。本研究的目的是测试这项技术,以评估老年 PWH 的跌倒风险:在一项横断面观察性研究中,研究人员使用经过验证的 BTrackS 平衡板对具有不同跌倒风险的感染者和非感染者进行了平衡评估。根据艾滋病毒血清状况对姿势稳定性进行了比较。采用多变量线性回归来研究姿势稳定性与跌倒风险平衡和虚弱状况的有效测量之间的关系:结果:在 34 名均≥50 岁的 PWH 和 30 名 PWoH 中,PWH 的姿势稳定性更差(35.4 厘米 vs 28.3 厘米,p= 0.07)。在多变量模型中,较差的姿势稳定性与过去 6 个月内曾跌倒(β=0.32,p=0.004)、跌倒效果较差(β=0.45,p=0.004)有关:在年长的重度残疾人和重度残疾人中,较差的姿势稳定性与跌倒风险的有效测量相关,包括跌倒史和较差的跌倒效果。评估姿势摇摆是一种很有前景的客观筛查老年残疾人跌倒风险的方法。
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Postural Stability as a Measure of Fall Risk in Older People with and without HIV.

As the number of older people with HIV (PWH) grows, accidental falls and their associated negative health outcomes are of increasing concern. Fall risk can be measured using novel screening tools such as evaluating postural stability using force plate technology. The aims of this study were to test this technology to assess fall risk among older PWH. In a cross-sectional, observational study of people without HIV (PWoH) with a range of fall risk, participants underwent balance assessment using the validated BTrackS balance plate. Postural stability was compared by HIV serostatus. Multivariable linear regressions were used to examine the relationship between postural stability and validated measures of fall risk balance and frailty status. Among 34 PWH and 30 PWoH, all ≥50 years, postural stability was worse among PWH (35.4 cm vs. 28.3 cm, p = .07). In multivariable models, worse postural stability was associated with reporting a fall in the past 6 months (β = 0.32, p = .004), worse fall efficacy (β = 0.45, p < .001), and being frail or prefrail (β = 0.26, p = .027). In multivariable models stratified by HIV serostatus, worse postural stability was significantly associated with worse fall efficacy (β = 0.53, p < .01) and lower balance confidence (β = -0.33, p =. 04) among PWH but not PWoH. Among older PWH and PWoH, worse postural stability was associated with validated measures of fall risk, including history of falls and poorer fall efficacy. Assessment of postural sway is a promising objective screening test for fall risk among older PWH.

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来源期刊
CiteScore
3.10
自引率
6.70%
发文量
201
审稿时长
3-6 weeks
期刊介绍: AIDS Research and Human Retroviruses was the very first AIDS publication in the field over 30 years ago, and today it is still the critical resource advancing research in retroviruses, including AIDS. The Journal provides the broadest coverage from molecular biology to clinical studies and outcomes research, focusing on developments in prevention science, novel therapeutics, and immune-restorative approaches. Cutting-edge papers on the latest progress and research advances through clinical trials and examination of targeted antiretroviral agents lead to improvements in translational medicine for optimal treatment outcomes. AIDS Research and Human Retroviruses coverage includes: HIV cure research HIV prevention science - Vaccine research - Systemic and Topical PreP Molecular and cell biology of HIV and SIV Developments in HIV pathogenesis and comorbidities Molecular biology, immunology, and epidemiology of HTLV Pharmacology of HIV therapy Social and behavioral science Rapid publication of emerging sequence information.
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