缩小球囊泵尺寸可降低腋主动脉内球囊泵故障风险

IF 3.1 3区 医学 Q2 ENGINEERING, BIOMEDICAL ASAIO Journal Pub Date : 2025-01-01 Epub Date: 2024-07-08 DOI:10.1097/MAT.0000000000002268
Sara S Inglis, Ardaas Kanwar, Hilda Gonzalez Bonilla, Swaiman Singh, Jennifer Y Pearson, Mohsin Abbas, Lori A Folkens, Narith N Ou, Philip J Spencer, Mauricio A Villavicencio, Alfredo L Clavell, Robert P Frantz, Andrew N Rosenbaum, Atta Behfar
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引用次数: 0

摘要

腋动脉主动脉内球囊反搏泵(axIABP)置入术已被用作心脏移植前的桥接方案。本研究评估了与 axIABP 支持相关的并发症,并介绍了将不良事件降至最低的方法。我们之前介绍了经皮置入 axIABP 的方法。然而,在 2017 年 9 月 1 日至 2019 年 9 月 26 日期间接受 axIABP 的患者(n = 32)显示出较高的球囊泵故障率(8/32;25%)和其他并发症发生率(总计 15/32;47%)。根据修订后的方案,64 名患者接受了连续治疗。与最初的队列相比,在人口统计学方面没有发现明显差异。干预后,球囊故障率(8/32,25% vs. 1/64,2%;P < 0.001)和支持期间的总并发症(15/32,47% vs. 10/64,16%;P = 0.0025)明显降低。随后对每种装置尺寸(40 毫升与≤ 34 毫升球囊)的总并发症进行分析,结果显示,使用较小装置的患者并发症明显减少(分别为 40% 与 13%;P = 0.0022)。这项研究为限制使用 axIABP 支持的患者的并发症提供了指导,有助于延长桥接支持的时间。
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Reduction in Balloon Pump Size Reduces Axillary Intraaortic Balloon Pump Failure Risk.

Axillary artery intra-aortic balloon pump (axIABP) placement has been implemented as a bridging solution before heart transplantation. This study evaluates complications associated with axIABP support and describes an approach to minimize adverse events. We previously described a percutaneous approach for axIABP placement. However, patients receiving axIABP between September 1, 2017, and September 26, 2019 (n = 32) demonstrated a high rate of balloon pump malfunction (8/32; 25%) and other complications (totaling 15/32; 47%). Sixty-four patients were sequentially treated under a revised protocol. Compared to the initial cohort, no significant differences in demographics were noted. A significant reduction in rate of balloon malfunction (8/32, 25% vs. 1/64, 2%; p < 0.001) and total complications (15/32, 47% vs. 10/64, 16%; p = 0.0025) during the period of support were noted after intervention. Subsequent analysis of total complications per device size (40 vs. ≤ 34 ml balloon) revealed significantly reduced complications in patients with smaller devices (40% vs. 13%, respectively; p = 0.0022). This study provides guidelines to limit complications in patients supported with axIABP, facilitating a protracted period of bridging support.

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来源期刊
ASAIO Journal
ASAIO Journal 医学-工程:生物医学
CiteScore
6.60
自引率
7.10%
发文量
651
审稿时长
4-8 weeks
期刊介绍: ASAIO Journal is in the forefront of artificial organ research and development. On the cutting edge of innovative technology, it features peer-reviewed articles of the highest quality that describe research, development, the most recent advances in the design of artificial organ devices and findings from initial testing. Bimonthly, the ASAIO Journal features state-of-the-art investigations, laboratory and clinical trials, and discussions and opinions from experts around the world. The official publication of the American Society for Artificial Internal Organs.
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