病例报告:多个转移性原发性耐多药结核脓肿

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH American Journal of Tropical Medicine and Hygiene Pub Date : 2024-07-09 Print Date: 2024-09-04 DOI:10.4269/ajtmh.23-0514
Megha Priyadarshi, Harish Pant, Sunit Sikdar, Sanjeev Sinha, Surabhi Vyas, Piyush Ranjan
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引用次数: 0

摘要

本病例报告介绍了一名 21 岁男性的非典型肺结核表现,他在过去 6 个月中出现双侧足跟、左肘和左手三指根部多处皮下肿胀。患者还出现了食欲不振和体重无意中减轻的症状。尽管最初怀疑是细菌性脓肿,但抗生素并没有带来明显改善。进一步检查发现红细胞沉降率升高,影像学检查结果提示骨髓炎。基因 Xpert 检测证实致病菌为耐多药结核分枝杆菌。患者接受了以贝达喹啉为基础的耐多药结核病治疗方案,结果肿胀缩小了。本报告强调了诊断和管理复杂的原发性多发性结核脓肿病例,尤其是耐药菌株病例所面临的挑战,强调了及时诊断和多学科管理对取得成功结果的重要性。
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Case Report: Multiple Metastatic Primary Multidrug-Resistant Tubercular Abscesses.

This case report presents an atypical manifestation of tuberculosis in a 21-year-old male who presented with multiple subcutaneous swellings in the bilateral heel, left elbow, and base of the left third finger for the previous 6 months. The patient also experienced loss of appetite and unintentional weight loss. Despite initial suspicion of bacterial abscesses, antibiotics did not lead to significant improvement. Further investigations revealed an elevated erythrocyte sedimentation rate and findings suggestive of osteomyelitis on imaging. Gene Xpert testing confirmed multidrug-resistant Mycobacterium tuberculosis as the causative agent. The patient was prescribed a bedaquiline-based multidrug-resistant tuberculosis regimen, which resulted in reduction in swelling size. This report highlights the challenges in diagnosing and managing complex cases of primary multiple tubercular abscesses, especially with drug-resistant strains, emphasizing the importance of timely diagnosis and multidisciplinary management for successful outcomes.

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来源期刊
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.20
自引率
3.00%
发文量
508
审稿时长
3 months
期刊介绍: The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine. The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development. The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal. Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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