{"title":"植物生物学中的微管模拟:一个即将成熟的领域","authors":"Marco Saltini, Eva E. Deinum","doi":"10.1016/j.pbi.2024.102596","DOIUrl":null,"url":null,"abstract":"<div><p>The plant cortical microtubule array is an important determinant of cell wall structure and, therefore, plant morphology and physiology. The array consists of dynamic microtubules interacting through frequent collisions. Since the discovery by Dixit and Cyr (2004) that the outcome of such collisions depends on the collision angle, computer simulations have been indispensable in studying array behaviour. Over the last decade, the available simulation tools have drastically improved: multiple high-quality simulation platforms exist with specific strengths and applications. Here, we review how these platforms differ on the critical aspects of microtubule nucleation, flexibility, and local orienting cues; and how such differences affect array behaviour. Building upon concepts and control parameters from theoretical models of collective microtubule behaviour, we conclude that all these factors matter in the debate about what is most important for orienting the array: local cues like mechanical stresses or global cues deriving from the cell geometry.</p></div>","PeriodicalId":11003,"journal":{"name":"Current opinion in plant biology","volume":"81 ","pages":"Article 102596"},"PeriodicalIF":8.3000,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1369526624000876/pdfft?md5=470eec62e61f9cc4bf4080afa30311af&pid=1-s2.0-S1369526624000876-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Microtubule simulations in plant biology: A field coming to maturity\",\"authors\":\"Marco Saltini, Eva E. Deinum\",\"doi\":\"10.1016/j.pbi.2024.102596\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The plant cortical microtubule array is an important determinant of cell wall structure and, therefore, plant morphology and physiology. The array consists of dynamic microtubules interacting through frequent collisions. Since the discovery by Dixit and Cyr (2004) that the outcome of such collisions depends on the collision angle, computer simulations have been indispensable in studying array behaviour. Over the last decade, the available simulation tools have drastically improved: multiple high-quality simulation platforms exist with specific strengths and applications. Here, we review how these platforms differ on the critical aspects of microtubule nucleation, flexibility, and local orienting cues; and how such differences affect array behaviour. Building upon concepts and control parameters from theoretical models of collective microtubule behaviour, we conclude that all these factors matter in the debate about what is most important for orienting the array: local cues like mechanical stresses or global cues deriving from the cell geometry.</p></div>\",\"PeriodicalId\":11003,\"journal\":{\"name\":\"Current opinion in plant biology\",\"volume\":\"81 \",\"pages\":\"Article 102596\"},\"PeriodicalIF\":8.3000,\"publicationDate\":\"2024-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1369526624000876/pdfft?md5=470eec62e61f9cc4bf4080afa30311af&pid=1-s2.0-S1369526624000876-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current opinion in plant biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1369526624000876\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current opinion in plant biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1369526624000876","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
植物皮层微管阵列是细胞壁结构的重要决定因素,因此也是植物形态和生理的重要决定因素。该阵列由通过频繁碰撞而相互作用的动态微管组成。自从 Dixit 和 Cyr(2004 年)发现这种碰撞的结果取决于碰撞角度后,计算机模拟就成为研究阵列行为不可或缺的工具。在过去的十年中,可用的模拟工具有了极大的改进:多种高质量的模拟平台具有特定的优势和应用。在此,我们回顾了这些平台在微管成核、柔性和局部定向线索等关键方面的差异,以及这些差异如何影响阵列行为。在集体微管行为理论模型的概念和控制参数的基础上,我们得出结论,所有这些因素在关于什么对阵列定向最重要的争论中都很重要:是机械应力等局部线索,还是源自细胞几何的全局线索。
Microtubule simulations in plant biology: A field coming to maturity
The plant cortical microtubule array is an important determinant of cell wall structure and, therefore, plant morphology and physiology. The array consists of dynamic microtubules interacting through frequent collisions. Since the discovery by Dixit and Cyr (2004) that the outcome of such collisions depends on the collision angle, computer simulations have been indispensable in studying array behaviour. Over the last decade, the available simulation tools have drastically improved: multiple high-quality simulation platforms exist with specific strengths and applications. Here, we review how these platforms differ on the critical aspects of microtubule nucleation, flexibility, and local orienting cues; and how such differences affect array behaviour. Building upon concepts and control parameters from theoretical models of collective microtubule behaviour, we conclude that all these factors matter in the debate about what is most important for orienting the array: local cues like mechanical stresses or global cues deriving from the cell geometry.
期刊介绍:
Current Opinion in Plant Biology builds on Elsevier's reputation for excellence in scientific publishing and long-standing commitment to communicating high quality reproducible research. It is part of the Current Opinion and Research (CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy - of editorial excellence, high-impact, and global reach - to ensure they are a widely read resource that is integral to scientists' workflow.