非常规石油和天然气 (UOG) 化学品暴露对人类健康的影响:毒理学文献范围综述。

IF 3 4区 医学 Q2 ENVIRONMENTAL SCIENCES Reviews on Environmental Health Pub Date : 2024-07-11 DOI:10.1515/reveh-2024-0076
Élyse Caron-Beaudoin, Hélène Akpo, Mary M Doyle-Waters, Lisa A Ronald, Michael Friesen, Tim Takaro, Karen Leven, Ulrike Meyer, Margaret J McGregor
{"title":"非常规石油和天然气 (UOG) 化学品暴露对人类健康的影响:毒理学文献范围综述。","authors":"Élyse Caron-Beaudoin, Hélène Akpo, Mary M Doyle-Waters, Lisa A Ronald, Michael Friesen, Tim Takaro, Karen Leven, Ulrike Meyer, Margaret J McGregor","doi":"10.1515/reveh-2024-0076","DOIUrl":null,"url":null,"abstract":"<p><p>Many chemicals associated with unconventional oil and natural gas (UOG) are known toxicants, leading to health concerns about the effects of UOG. Our objective was to conduct a scoping review of the toxicological literature to assess the effects of UOG chemical exposures in models relevant to human health. We searched databases for primary research studies published in English or French between January 2000 and June 2023 on UOG-related toxicology studies. Two reviewers independently screened abstracts and full texts to determine inclusion. Seventeen studies met our study inclusion criteria. Nine studies used solely <i>in vitro</i> models, while six conducted their investigation solely in animal models. Two studies incorporated both types of models. Most studies used real water samples impacted by UOG or lab-made mixtures of UOG chemicals to expose their models. Most <i>in vitro</i> models used human cells in monocultures, while all animal studies were conducted in rodents. All studies detected significant deleterious effects associated with exposure to UOG chemicals or samples, including endocrine disruption, carcinogenicity, behavioral changes and metabolic alterations. Given the plausibility of causal relationships between UOG chemicals and adverse health outcomes highlighted in this review, future risk assessment studies should focus on measuring exposure to UOG chemicals in human populations.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The human health effects of unconventional oil and gas (UOG) chemical exposures: a scoping review of the toxicological literature.\",\"authors\":\"Élyse Caron-Beaudoin, Hélène Akpo, Mary M Doyle-Waters, Lisa A Ronald, Michael Friesen, Tim Takaro, Karen Leven, Ulrike Meyer, Margaret J McGregor\",\"doi\":\"10.1515/reveh-2024-0076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Many chemicals associated with unconventional oil and natural gas (UOG) are known toxicants, leading to health concerns about the effects of UOG. Our objective was to conduct a scoping review of the toxicological literature to assess the effects of UOG chemical exposures in models relevant to human health. We searched databases for primary research studies published in English or French between January 2000 and June 2023 on UOG-related toxicology studies. Two reviewers independently screened abstracts and full texts to determine inclusion. Seventeen studies met our study inclusion criteria. Nine studies used solely <i>in vitro</i> models, while six conducted their investigation solely in animal models. Two studies incorporated both types of models. Most studies used real water samples impacted by UOG or lab-made mixtures of UOG chemicals to expose their models. Most <i>in vitro</i> models used human cells in monocultures, while all animal studies were conducted in rodents. All studies detected significant deleterious effects associated with exposure to UOG chemicals or samples, including endocrine disruption, carcinogenicity, behavioral changes and metabolic alterations. Given the plausibility of causal relationships between UOG chemicals and adverse health outcomes highlighted in this review, future risk assessment studies should focus on measuring exposure to UOG chemicals in human populations.</p>\",\"PeriodicalId\":21165,\"journal\":{\"name\":\"Reviews on Environmental Health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Reviews on Environmental Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1515/reveh-2024-0076\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews on Environmental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1515/reveh-2024-0076","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0

摘要

与非常规石油和天然气 (UOG) 相关的许多化学品都是已知的有毒物质,这导致了人们对 UOG 的健康影响的担忧。我们的目标是对毒理学文献进行一次范围界定,以评估在与人类健康相关的模型中接触 UOG 化学物质的影响。我们在数据库中搜索了 2000 年 1 月至 2023 年 6 月间以英文或法文发表的关于 UOG 相关毒理学研究的主要研究报告。两名审稿人独立筛选摘要和全文,以确定是否纳入研究。17项研究符合我们的研究纳入标准。九项研究仅使用了体外模型,六项研究仅使用了动物模型。有两项研究同时使用了这两种模型。大多数研究使用受 UOG 影响的真实水样或实验室制造的 UOG 化学品混合物来暴露其模型。大多数体外模型使用的是单培养的人体细胞,而所有动物研究都是在啮齿动物身上进行的。所有研究都检测到与接触 UOG 化学品或样本有关的重大有害影响,包括内分泌干扰、致癌性、行为变化和新陈代谢改变。鉴于本综述中强调的 UOG 化学品与不良健康结果之间的因果关系的合理性,未来的风险评估研究应侧重于测量人类暴露于 UOG 化学品的情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The human health effects of unconventional oil and gas (UOG) chemical exposures: a scoping review of the toxicological literature.

Many chemicals associated with unconventional oil and natural gas (UOG) are known toxicants, leading to health concerns about the effects of UOG. Our objective was to conduct a scoping review of the toxicological literature to assess the effects of UOG chemical exposures in models relevant to human health. We searched databases for primary research studies published in English or French between January 2000 and June 2023 on UOG-related toxicology studies. Two reviewers independently screened abstracts and full texts to determine inclusion. Seventeen studies met our study inclusion criteria. Nine studies used solely in vitro models, while six conducted their investigation solely in animal models. Two studies incorporated both types of models. Most studies used real water samples impacted by UOG or lab-made mixtures of UOG chemicals to expose their models. Most in vitro models used human cells in monocultures, while all animal studies were conducted in rodents. All studies detected significant deleterious effects associated with exposure to UOG chemicals or samples, including endocrine disruption, carcinogenicity, behavioral changes and metabolic alterations. Given the plausibility of causal relationships between UOG chemicals and adverse health outcomes highlighted in this review, future risk assessment studies should focus on measuring exposure to UOG chemicals in human populations.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Reviews on Environmental Health
Reviews on Environmental Health Social Sciences-Health (social science)
CiteScore
7.20
自引率
2.60%
发文量
75
期刊介绍: Reviews on Environmental Health (REVEH) is an international peer-reviewed journal that aims to fill the need for publication of review articles on hot topics in the field of environmental health. Reviews on Environmental Health aims to be an inspiring forum for scientists, environmentalists, physicians, engineers, and students who are concerned with aspects of human health, including quality of life, that are determined by physiological and psychosociological interactions between man and physical, chemical, biological, and social factors in the environment. Reviews on Environmental Health is an important niche served by no other journal, that’s being a site where thoughtful reviews can be published on a variety of subjects related to both health and environment. One challenge is to bridge the research on environmental causes of disease with the clinical practice of medicine. Reviews on Environmental Health is a source of integrated information on environment and health subjects that will be of value to the broad scientific community, whether students, junior and senior professionals, or clinicians.
期刊最新文献
A systematic review and quality assessment of estimated daily intake of microplastics through food. Comprehensive approach to clinical decision-making strategy, illustrated by the Gulf War. A review of the potential adverse health impacts of atrazine in humans. Semi-IPN polysaccharide-based hydrogels for effective removal of heavy metal ions and dyes from wastewater: a comprehensive investigation of performance and adsorption mechanism. Tributyltin induces apoptosis in mammalian cells in vivo: a scoping review.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1