{"title":"在回旋加速器生产碘-123/124 过程中冷却固体靶的新方法","authors":"S. S. Salodkin, V. V. Sokhoreva","doi":"10.1134/S0020441224700520","DOIUrl":null,"url":null,"abstract":"<p>The possibility of cooling a ТеО<sub>2</sub> target during production of radionuclides based on <sup>123/124</sup>I has been investigated. Different cooling methods used in production of radiopharmaceuticals, as well as their advantages and drawbacks, are considered. A new method is proposed for cooling the front side of a solid target (a TeO<sub>2</sub> layer) by a fine-dispersed flow of sprayed water. Experiments have been conducted at the cyclotron of the Tomsk Polytechnic University on the cooling of a TeO<sub>2</sub> target irradiated by an accelerated deuteron beam. As a result, at a water flow rate of 15 mL/min and a spraying plume diameter of 38 mm, the beam thermal energy of 113 W has been dissipated at a target surface temperature of 120−130°C.</p>","PeriodicalId":587,"journal":{"name":"Instruments and Experimental Techniques","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A New Method for Cooling a Solid Target during Iodine-123/124 Production at a Cyclotron\",\"authors\":\"S. S. Salodkin, V. V. Sokhoreva\",\"doi\":\"10.1134/S0020441224700520\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The possibility of cooling a ТеО<sub>2</sub> target during production of radionuclides based on <sup>123/124</sup>I has been investigated. Different cooling methods used in production of radiopharmaceuticals, as well as their advantages and drawbacks, are considered. A new method is proposed for cooling the front side of a solid target (a TeO<sub>2</sub> layer) by a fine-dispersed flow of sprayed water. Experiments have been conducted at the cyclotron of the Tomsk Polytechnic University on the cooling of a TeO<sub>2</sub> target irradiated by an accelerated deuteron beam. As a result, at a water flow rate of 15 mL/min and a spraying plume diameter of 38 mm, the beam thermal energy of 113 W has been dissipated at a target surface temperature of 120−130°C.</p>\",\"PeriodicalId\":587,\"journal\":{\"name\":\"Instruments and Experimental Techniques\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2024-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Instruments and Experimental Techniques\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S0020441224700520\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Instruments and Experimental Techniques","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1134/S0020441224700520","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
摘要 研究了在以 123/124I 为基础的放射性核素生产过程中冷却ТеО2 靶件的可能性。研究考虑了用于生产放射性药物的不同冷却方法及其优缺点。提出了一种新方法，即通过细分散的喷射水流冷却固体靶（TeO2 层）的正面。在托木斯克理工大学的回旋加速器上进行了用加速氘核光束冷却 TeO2 靶件的实验。结果表明，在水流速度为 15 mL/min 和喷射羽流直径为 38 mm 的条件下，113 W 的光束热能在靶表面温度为 120-130°C 时被耗散。
A New Method for Cooling a Solid Target during Iodine-123/124 Production at a Cyclotron
The possibility of cooling a ТеО2 target during production of radionuclides based on 123/124I has been investigated. Different cooling methods used in production of radiopharmaceuticals, as well as their advantages and drawbacks, are considered. A new method is proposed for cooling the front side of a solid target (a TeO2 layer) by a fine-dispersed flow of sprayed water. Experiments have been conducted at the cyclotron of the Tomsk Polytechnic University on the cooling of a TeO2 target irradiated by an accelerated deuteron beam. As a result, at a water flow rate of 15 mL/min and a spraying plume diameter of 38 mm, the beam thermal energy of 113 W has been dissipated at a target surface temperature of 120−130°C.
期刊介绍：
Instruments and Experimental Techniques is an international peer reviewed journal that publishes reviews describing advanced methods for physical measurements and techniques and original articles that present techniques for physical measurements, principles of operation, design, methods of application, and analysis of the operation of physical instruments used in all fields of experimental physics and when conducting measurements using physical methods and instruments in astronomy, natural sciences, chemistry, biology, medicine, and ecology.
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