特应性皮炎与肠道微生物群相关性的研究进展

IF 1.9 4区医学 Q3 DERMATOLOGY Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-07-08 DOI:10.2147/ccid.s442551

Qiuyu Mao, Xinyi Wang, Haibin Cai, Jingyi Yang, Yiwen Zhang, Wei Min, Qihong Qian, Yibin Zeng

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引用次数: 0

摘要

摘要：特应性皮炎（AD）是一种常见的皮肤病，其发病机制尚未完全阐明。肠道微生物群是人体内最大的微生态系统，会影响免疫系统和皮肤屏障功能。最近的研究表明，除了环境因素、皮肤屏障、遗传因素和免疫反应外，肠道微生物群紊乱也可能导致 AD。本综述阐述了特应性皮炎与肠道微生物群的相关性，以及通过靶向肠道微生物群治疗特应性皮炎的现有研究现状。

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Research Progress on the Correlation of Atopic Dermatitis with Gut Microbiota

Abstract: Atopic dermatitis (AD) is a common skin disease, the pathogenesis of which has not been fully elucidated. The gut microbiota is the largest micro-ecosystem in the human body that affects the immune system and skin barrier function. Recent studies have shown that in addition to the environmental factors, skin barrier, genetic factors and immune response, gut microbiota disturbance may also cause AD. This review described the correlation of AD with gut microbiota and existing research status of AD treatment via targeting gut microbiota.

Keywords: atopic dermatitis, gut microbiota, fecal microbiota transplantation

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.