用于电子医学的生物可吸收聚合物

IF 7.9 2区 综合性期刊 Q1 CHEMISTRY, MULTIDISCIPLINARY Cell Reports Physical Science Pub Date : 2024-07-09 DOI:10.1016/j.xcrp.2024.102099
Jung Hwangbo, Hyungho Seo, Gyuhyeon Sim, Raudel Avila, Malavika Nair, Byeonggwan Kim, Yeonsik Choi
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引用次数: 0

摘要

在材料科学领域,植入式传感器和刺激器正以瞬态电子学或俗称的 "生物可吸收电子医学 "的形式迅速发展。这种开创性的技术具有明显的优势,因为它可以在人体内溶解,从而避免了永久性植入物的必要性以及随之而来的与移除手术相关的风险。在寻求制造具有持久体内稳定性的生物可吸收设备的过程中,生物可吸收聚合物作为电子平台的封装物、基底和电介质的关键作用变得显而易见。本文全面评述了潜在的生物可吸收聚合物材料,仔细研究了它们在确保电子药物的耐用性和性能方面的作用。本综述的核心内容扎根于生物可吸收聚合物的基本方面,包括其合成、降解机制以及机械和热行为。随后的讨论阐明了生物可吸收聚合物在电子医学领域应用的复杂性,包括透水性、界面粘附性以及与生物组织的相互作用。此外,本综述还介绍了生物可吸收聚合物在电子植入物中的实际应用,并特别强调了推动电子封装技术进步的基本研究动机。总之,本综述以敏锐的眼光审视了聚合物材料的前景,为生物可吸收电子系统领域的突破铺平了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Bioresorbable polymers for electronic medicine

In the arena of materials science, the landscape of implantable sensors and stimulators is rapidly advancing, taking the form of transient electronics or what is colloquially known as “bioresorbable electronic medicine.” This pioneering technology holds a distinct advantage, as it dissolves within the human body, obviating the necessity for permanent implants and the attendant risks associated with removal surgeries. In the quest to fabricate bioresorbable devices with enduring in vivo stability, the pivotal role of bioresorbable polymers becomes apparent, serving as encapsulants, substrates, and dielectrics for electronic platforms. This paper provides a comprehensive review of potential bioresorbable polymeric materials, meticulously scrutinizing their utility in ensuring the durability and performance of electronic medicines. The core of this review is firmly rooted in the fundamental aspects of bioresorbable polymers, encompassing their synthesis, degradation mechanisms, and mechanical and thermal behaviors. Subsequent discussions illuminate the intricacies surrounding the utilization of bioresorbable polymers in the realm of electronic medicine, including water permeability, interfacial adhesion, and interactions with biological tissues. Furthermore, this exposition introduces practical deployment of bioresorbable polymers in electronic implants, with a particular emphasis on the underlying research motivations driving progress in electronic encapsulation. In conclusion, this comprehensive review casts a discerning eye on the horizon of polymeric materials, paving the way for breakthroughs in the field of bioresorbable electronic systems.

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来源期刊
Cell Reports Physical Science
Cell Reports Physical Science Energy-Energy (all)
CiteScore
11.40
自引率
2.20%
发文量
388
审稿时长
62 days
期刊介绍: Cell Reports Physical Science, a premium open-access journal from Cell Press, features high-quality, cutting-edge research spanning the physical sciences. It serves as an open forum fostering collaboration among physical scientists while championing open science principles. Published works must signify significant advancements in fundamental insight or technological applications within fields such as chemistry, physics, materials science, energy science, engineering, and related interdisciplinary studies. In addition to longer articles, the journal considers impactful short-form reports and short reviews covering recent literature in emerging fields. Continually adapting to the evolving open science landscape, the journal reviews its policies to align with community consensus and best practices.
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