{"title":"细胞间嘈杂信息动态的灵活性","authors":"Ismail Qunbar, Michael Vennettilli, Amir Erez","doi":"arxiv-2407.06556","DOIUrl":null,"url":null,"abstract":"Exchange of molecules allows cells to exchange information. How robust is the\ninformation to changes in cell parameters? We use a mapping between the\nstochastic dynamics of two cells sharing a stimulatory molecule, and parameters\nakin to an extension of Landau's equilibrium phase transition theory. We show\nthat different single-cell dynamics lead to the same dynamical response -- a\nflexibility that cells can use. The companion equilibrium Landau model behaves\nsimilarly, thereby describing the dynamics of information in a broad class of\nmodels with coupled order parameters.","PeriodicalId":501325,"journal":{"name":"arXiv - QuanBio - Molecular Networks","volume":"36 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Flexibility in noisy cell-to-cell information dynamics\",\"authors\":\"Ismail Qunbar, Michael Vennettilli, Amir Erez\",\"doi\":\"arxiv-2407.06556\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Exchange of molecules allows cells to exchange information. How robust is the\\ninformation to changes in cell parameters? We use a mapping between the\\nstochastic dynamics of two cells sharing a stimulatory molecule, and parameters\\nakin to an extension of Landau's equilibrium phase transition theory. We show\\nthat different single-cell dynamics lead to the same dynamical response -- a\\nflexibility that cells can use. The companion equilibrium Landau model behaves\\nsimilarly, thereby describing the dynamics of information in a broad class of\\nmodels with coupled order parameters.\",\"PeriodicalId\":501325,\"journal\":{\"name\":\"arXiv - QuanBio - Molecular Networks\",\"volume\":\"36 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"arXiv - QuanBio - Molecular Networks\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/arxiv-2407.06556\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv - QuanBio - Molecular Networks","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/arxiv-2407.06556","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Flexibility in noisy cell-to-cell information dynamics
Exchange of molecules allows cells to exchange information. How robust is the
information to changes in cell parameters? We use a mapping between the
stochastic dynamics of two cells sharing a stimulatory molecule, and parameters
akin to an extension of Landau's equilibrium phase transition theory. We show
that different single-cell dynamics lead to the same dynamical response -- a
flexibility that cells can use. The companion equilibrium Landau model behaves
similarly, thereby describing the dynamics of information in a broad class of
models with coupled order parameters.