基于核磁共振的植物代谢组学的最新进展:技术、工具和分析方法。

IF 4.2 2区 化学 Q1 CHEMISTRY, ANALYTICAL Critical reviews in analytical chemistry Pub Date : 2024-07-11 DOI:10.1080/10408347.2024.2375314
Nitish Kumar, Vikas Jaitak
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引用次数: 0

摘要

植物代谢组学是植物生物学中一个快速发展的领域,致力于全面探索植物系统中错综复杂的小分子。这需要精确收集全面的化学数据,检测大量代谢物,并确保准确的分子鉴定。核磁共振(NMR)光谱具有详细的化学洞察力,是获取代谢物概况的关键。它的广泛应用横跨各个研究学科,有助于理解化学反应、动力学和分子特征。生物技术的进步进一步扩大了 NMR 在代谢组学中的应用,特别是在农业、医学和药理学等不同领域中确定疾病生物标志物方面。本综述涵盖了基于核磁共振的代谢组学的各个阶段,包括历史方面和局限性,以及样品制备、数据采集、光谱处理、分析及其应用部分。
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Recent Advancement in NMR Based Plant Metabolomics: Techniques, Tools, and Analytical Approaches.

Plant metabolomics, a rapidly advancing field within plant biology, is dedicated to comprehensively exploring the intricate array of small molecules in plant systems. This entails precisely gathering comprehensive chemical data, detecting numerous metabolites, and ensuring accurate molecular identification. Nuclear magnetic resonance (NMR) spectroscopy, with its detailed chemical insights, is crucial in obtaining metabolite profiles. Its widespread application spans various research disciplines, aiding in comprehending chemical reactions, kinetics, and molecule characterization. Biotechnological advancements have further expanded NMR's utility in metabolomics, particularly in identifying disease biomarkers across diverse fields such as agriculture, medicine, and pharmacology. This review covers the stages of NMR-based metabolomics, including historical aspects and limitations, with sample preparation, data acquisition, spectral processing, analysis, and their application parts.

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来源期刊
CiteScore
12.00
自引率
4.00%
发文量
137
审稿时长
6 months
期刊介绍: Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area. This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following: · chemical analysis; · instrumentation; · chemometrics; · analytical biochemistry; · medicinal analysis; · forensics; · environmental sciences; · applied physics; · and material science.
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