光生物调节疗法治疗某些非表皮肿瘤的安全性实验研究。

IF 2.1 4区医学 Q3 ENGINEERING, BIOMEDICAL Lasers in Medical Science Pub Date : 2024-07-13 DOI:10.1007/s10103-024-04121-z

Fang Nie, Yu Ji, Hao Sun, Zeqian Lee, Yan Zhang, Wei Han, YuChuan Ding

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引用次数: 0

摘要

本研究探讨了不同波长的光生物调控（PBM）对非表皮癌细胞的影响。研究利用三种激光方案（650 nm、810 nm 和 915 nm），探讨了细胞毒性效应、ROS 生成和细胞迁移。结果显示，不同细胞系的反应各不相同，810 nm 的 PBM 能诱导大量 ROS 并抑制 PAN-1 细胞的迁移。研究表明，PBM 在非浅表癌症中具有潜在的治疗用途，强调了在临床环境中进一步探索的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Experimental study on the safety of photobiologic regulation therapy in the treatment of some non-epidermal tumors.

This study investigates the impact of Photobiomodulation (PBM) at different wavelengths on non-superficial cancer cells. Utilizing three laser protocols (650 nm, 810 nm, and 915 nm), the research explores cytotoxic effects, ROS generation, and cell migration. Results reveal varied responses across cell lines, with 810 nm PBM inducing significant ROS levels and inhibiting PAN-1 cell migration. The study suggests potential therapeutic applications for PBM in non-superficial cancers, emphasizing the need for further exploration in clinical settings.

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来源期刊

Lasers in Medical Science 医学-工程：生物医学

CiteScore

4.50

自引率

4.80%

发文量

192

审稿时长

3-8 weeks

期刊介绍： Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics. The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.