Dr. Victor Montalli , Ms. Larissa Agatti , Ms. Carolina Netto , Ms. Stella Paes , Dr. Marcelo Sperandio , Dr. Paulo Moraes
{"title":"治疗骨坏死的综合方法：光动力疗法和高压氧舱的协同作用","authors":"Dr. Victor Montalli , Ms. Larissa Agatti , Ms. Carolina Netto , Ms. Stella Paes , Dr. Marcelo Sperandio , Dr. Paulo Moraes","doi":"10.1016/j.oooo.2024.04.033","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>This study explores an innovative therapeutic strategy by integrating photodynamic therapy (PDT) and hyperbaric chamber treatment for effective osteonecrosis management.</p></div><div><h3>Case Report</h3><p>A 65-year-old male with metastatic prostate cancer, receiving Zometa® treatment, presented bilateral mandibular exposed bone, causing pain. A multidisciplinary approach was employed, using topical antiseptics, PDT sessions, and hyperbaric therapy to address the complex condition.</p></div><div><h3>Conclusions</h3><p>During follow-up, the patient underwent sequestrectomy due to bone sequestration. Subsequent tissue repair occurred smoothly, and the patient remained asymptomatic for three years post-treatment. This integrated approach shows promise in managing osteonecrosis, addressing microbial burden, and enhancing tissue repair. PDT and hyperbaric therapy offer a comprehensive solution for osteonecrosis. Further investigations are essential to validate and refine this approach, potentially establishing it as a standard protocol in oral medicine.</p></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.0000,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Integrated Approach for the Management of Osteonecrosis: Photodynamic Therapy and Hyperbaric Chamber Synergy\",\"authors\":\"Dr. Victor Montalli , Ms. Larissa Agatti , Ms. Carolina Netto , Ms. Stella Paes , Dr. Marcelo Sperandio , Dr. Paulo Moraes\",\"doi\":\"10.1016/j.oooo.2024.04.033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>This study explores an innovative therapeutic strategy by integrating photodynamic therapy (PDT) and hyperbaric chamber treatment for effective osteonecrosis management.</p></div><div><h3>Case Report</h3><p>A 65-year-old male with metastatic prostate cancer, receiving Zometa® treatment, presented bilateral mandibular exposed bone, causing pain. A multidisciplinary approach was employed, using topical antiseptics, PDT sessions, and hyperbaric therapy to address the complex condition.</p></div><div><h3>Conclusions</h3><p>During follow-up, the patient underwent sequestrectomy due to bone sequestration. Subsequent tissue repair occurred smoothly, and the patient remained asymptomatic for three years post-treatment. This integrated approach shows promise in managing osteonecrosis, addressing microbial burden, and enhancing tissue repair. PDT and hyperbaric therapy offer a comprehensive solution for osteonecrosis. Further investigations are essential to validate and refine this approach, potentially establishing it as a standard protocol in oral medicine.</p></div>\",\"PeriodicalId\":49010,\"journal\":{\"name\":\"Oral Surgery Oral Medicine Oral Pathology Oral Radiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-07-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral Surgery Oral Medicine Oral Pathology Oral Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212440324002104\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212440324002104","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Integrated Approach for the Management of Osteonecrosis: Photodynamic Therapy and Hyperbaric Chamber Synergy
Introduction
This study explores an innovative therapeutic strategy by integrating photodynamic therapy (PDT) and hyperbaric chamber treatment for effective osteonecrosis management.
Case Report
A 65-year-old male with metastatic prostate cancer, receiving Zometa® treatment, presented bilateral mandibular exposed bone, causing pain. A multidisciplinary approach was employed, using topical antiseptics, PDT sessions, and hyperbaric therapy to address the complex condition.
Conclusions
During follow-up, the patient underwent sequestrectomy due to bone sequestration. Subsequent tissue repair occurred smoothly, and the patient remained asymptomatic for three years post-treatment. This integrated approach shows promise in managing osteonecrosis, addressing microbial burden, and enhancing tissue repair. PDT and hyperbaric therapy offer a comprehensive solution for osteonecrosis. Further investigations are essential to validate and refine this approach, potentially establishing it as a standard protocol in oral medicine.
期刊介绍：
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.
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