校本防龋的筛查和治疗时间:随机临床试验

Tamarinda J. Barry Godin, Gabriel Hawthorne, Radhika Shah, Ryan Richard Ruff
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摘要

背景:校本龋齿预防可增加代表人数不足的儿童获得牙科服务的机会,并降低蛀牙风险。方法CariedAway研究是一项纵向实用随机试验,试验内容包括作为学校龋病预防项目一部分的二胺氟化银(SDF)、氟化清漆、牙齿密封剂和无损伤修复(ART)。通过使用电子健康记录软件和可重复的程序,我们估算出了筛查和治疗项目参与者所需的总时间。我们使用线性回归和聚类标准误差估算法确定了不同干预措施、提供者(注册护士和牙科保健师)、牙列组合和龋齿负担在初始治疗时的差异,并使用线性混合效应模型估算了纵向效应。结果共有 7418 名儿童参加了 CariedAway 试验,其中 7176 人(97%)记录了筛查和治疗时间的有效数据。接受 SDF 和氟化物清漆治疗的儿童的总体治疗时间为 283 秒(SD=739),而接受牙齿密封剂和 ART 治疗的儿童的总体治疗时间为 753 秒(SD=2166)。在首次项目就诊时,使用 SDF 的治疗时间明显短于密封剂和 ART(B = -458.8,95% CI = -650.1,-266.8),并且治疗时间随着每次后续观察而减少(B = -51.9,95% CI = -68.4,-35.4)。随着每个儿童龋齿数量的增加,治疗时间也明显增加,注册护士和牙科保健师使用 SDF 的治疗时间没有差异。结论有关项目后勤和治疗时间的可靠数据可支持校本龋病预防的可持续性。未来的校本密封剂和 SDF 项目可以利用这些结果来估算预期治疗的总覆盖范围和有效性。
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Screening and treatment time in school-based caries prevention: A randomized clinical trial
Background: School-based caries prevention can increase access to dental services for underrepresented children and reduce the risk of tooth decay. Methods: The CariedAway study was a longitudinal pragmatic randomized trial of silver diamine fluoride (SDF), fluoride varnish, dental sealants, and atraumatic restorations (ART) provided as part of a school caries prevention program. Using electronic health record software and reproducible procedures, we estimated the total time required to screen and treat program participants. Differences at initial treatment between interventions, provider (registered nurse and dental hygienist), dentition mix, and caries burden were determined using linear regression with cluster standard error estimation, and longitudinal effects were estimated using linear mixed effects models. Results: A total of 7418 children were enrolled in the CariedAway trial, of which 7176 (97%) had viable data recorded for screening and treatment time. Overall treatment time for children receiving SDF and fluoride varnish was 283 seconds (SD=739), compared to 753 seconds (SD=2166) for children receiving dental sealants and ART. At the initial program visit, treatment time using SDF was significantly shorter than sealants and ART (B = -458.8, 95% CI = -650.1, -266.8) and treatment time decreased with each subsequent observation (B = -51.9, 95% CI = -68.4, -35.4). Treatment time significantly increased as the number of carious teeth per child increased, and there were no differences in treatment time using SDF between registered nurses and dental hygienists. Conclusions: The sustainability of school-based caries prevention can be supported by robust data on program logistics and treatment time. These results can be leveraged by future school-based sealant and SDF programs to estimate the total reach and effectiveness of intended treatments.
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