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{"title":"利用含有纳米银的纳米管和体外生物陶瓷增强耐磨性、抗菌性能和生物相容性","authors":"Qingge Wang, Jia Liu, Hong Wu, Jingbo Liu, Yaojia Ren, Luxin Liang, Xinxin Yan, Ian Baker, Shifeng Liu, V. V. Uglov, Chengliang Yang, Liqiang Wang","doi":"10.1007/s42242-024-00279-1","DOIUrl":null,"url":null,"abstract":"<p>理想的钛基关节植入物应避免力屏蔽, 且具有良好的生物活性和抗感染性能。为满足这些要求, 研究人员以低弹性模量合金Ti–35Nb–2Ta–3Zr为基底, 采用阳极化、沉积和旋涂等方法制备含有生物陶瓷和银离子的功能涂层, 并将其涂覆在TiO<sub>2</sub>纳米管 ((80 ± 20) nm 和(150 ± 40) nm) 表面。研究了生物陶瓷 (nano-β-TCP, micro-HA, meso-CaSiO<sub>3</sub>) 和Ag纳米颗粒 ((50 ± 20) nm) 对纳米管的抗菌活性、摩擦、腐蚀和早期体外成骨行为的影响。摩擦和腐蚀结果表明, 磨损率和腐蚀速率与纳米管表面形貌密切相关。由于粘着磨损和磨粒磨损, 生物陶瓷micro-HA 表现出优异的耐磨性, 磨损率为(1.26 ± 0.06)×10<sup>–3</sup> mm<sup>3</sup>/(N m)。生物陶瓷meso-CaSiO<sub>3</sub>显示出良好的细胞粘附、增殖能力和碱性磷酸酶活性。含有纳米银的涂层具有良好的抗菌活性, 对大肠杆菌的抗菌率 ≥ 89.5%。研究结果表明, 该功能涂层具有加速成骨的潜力。</p>","PeriodicalId":48627,"journal":{"name":"Bio-Design and Manufacturing","volume":null,"pages":null},"PeriodicalIF":8.1000,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhanced wear resistance, antibacterial performance, and biocompatibility using nanotubes containing nano-Ag and bioceramics in vitro\",\"authors\":\"Qingge Wang, Jia Liu, Hong Wu, Jingbo Liu, Yaojia Ren, Luxin Liang, Xinxin Yan, Ian Baker, Shifeng Liu, V. V. Uglov, Chengliang Yang, Liqiang Wang\",\"doi\":\"10.1007/s42242-024-00279-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>理想的钛基关节植入物应避免力屏蔽, 且具有良好的生物活性和抗感染性能。为满足这些要求, 研究人员以低弹性模量合金Ti–35Nb–2Ta–3Zr为基底, 采用阳极化、沉积和旋涂等方法制备含有生物陶瓷和银离子的功能涂层, 并将其涂覆在TiO<sub>2</sub>纳米管 ((80 ± 20) nm 和(150 ± 40) nm) 表面。研究了生物陶瓷 (nano-β-TCP, micro-HA, meso-CaSiO<sub>3</sub>) 和Ag纳米颗粒 ((50 ± 20) nm) 对纳米管的抗菌活性、摩擦、腐蚀和早期体外成骨行为的影响。摩擦和腐蚀结果表明, 磨损率和腐蚀速率与纳米管表面形貌密切相关。由于粘着磨损和磨粒磨损, 生物陶瓷micro-HA 表现出优异的耐磨性, 磨损率为(1.26 ± 0.06)×10<sup>–3</sup> mm<sup>3</sup>/(N m)。生物陶瓷meso-CaSiO<sub>3</sub>显示出良好的细胞粘附、增殖能力和碱性磷酸酶活性。含有纳米银的涂层具有良好的抗菌活性, 对大肠杆菌的抗菌率 ≥ 89.5%。研究结果表明, 该功能涂层具有加速成骨的潜力。</p>\",\"PeriodicalId\":48627,\"journal\":{\"name\":\"Bio-Design and Manufacturing\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":8.1000,\"publicationDate\":\"2024-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bio-Design and Manufacturing\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s42242-024-00279-1\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bio-Design and Manufacturing","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s42242-024-00279-1","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
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