基于仿生多复合物的新型磁性胶体系统

IF 0.7 Q4 CHEMISTRY, MULTIDISCIPLINARY Moscow University Chemistry Bulletin Pub Date : 2024-07-11 DOI:10.3103/S0027131424700135

I. V. Grigoryan, V. V. Spiridonov, A. M. Adelyanov, Yu. A. Koksharov, K. V. Potapenkov, I. V. Taranov, G. B. Khomutov, A. A. Yaroslavov

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摘要

摘要本文介绍了有望用作药用化合物载体的新型胶体系统，它们是以不同分子量的聚丙烯酸分子和生物多胺为基础的聚合物复合物，另外还用磁性氧化铁纳米粒子进行了改性。我们确定了由此产生的聚合物复合物的主要理化特性。证明了在聚合体中加入多柔比星药用化合物的可能性，并研究了用磁性氧化铁纳米颗粒功能化的聚合体的磁性。

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New Magnetic Colloidal Systems Based on Biomimetic Polycomplexes

This paper presents new colloidal systems that have prospects for use as carriers of medicinal compounds and are polymer complexes based on polyacrylic acid molecules of various molecular weights and biogenic polyamine, additionally modified with magnetic iron oxide nanoparticles. The main physicochemical characteristics of the resulting polycomplexes are determined. The possibility of incorporating a doxorubicin medicinal compound in the polycomplexes is demonstrated, and the magnetic properties of the polycomplexes functionalized with magnetic iron oxide nanoparticles are studied.

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来源期刊

Moscow University Chemistry Bulletin CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

1.30

自引率

14.30%

发文量

期刊介绍： Moscow University Chemistry Bulletin is a journal that publishes review articles, original research articles, and short communications on various areas of basic and applied research in chemistry, including medical chemistry and pharmacology.