膜力学反馈在膜交通中的作用

IF 6 2区 生物学 Q1 CELL BIOLOGY Current Opinion in Cell Biology Pub Date : 2024-07-16 DOI:10.1016/j.ceb.2024.102401
Jian Liu
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引用次数: 0

摘要

综合最近的研究进展,我们提出了关于膜曲率、张力和弯曲能的局部调节如何定义膜交通过程反馈控制的观点。我们推测了内吞和外-内吞耦合中不同膜力学介导的反馈的潜在机制及其背后的控制逻辑。我们阐述了前进的道路,包括理论考虑的开放性问题和实验验证的巨大挑战。
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Roles of membrane mechanics-mediated feedback in membrane traffic

Synthesizing the recent progresses, we present our perspectives on how local modulations of membrane curvature, tension, and bending energy define the feedback controls over membrane traffic processes. We speculate the potential mechanisms of, and the control logic behind, the different membrane mechanics-mediated feedback in endocytosis and exo-endocytosis coupling. We elaborate the path forward with the open questions for theoretical considerations and the grand challenges for experimental validations.

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来源期刊
Current Opinion in Cell Biology
Current Opinion in Cell Biology 生物-细胞生物学
CiteScore
14.60
自引率
1.30%
发文量
79
审稿时长
93 days
期刊介绍: Current Opinion in Cell Biology (COCEBI) is a highly respected journal that specializes in publishing authoritative, comprehensive, and systematic reviews in the field of cell biology. The journal's primary aim is to provide a clear and readable synthesis of the latest advances in cell biology, helping specialists stay current with the rapidly evolving field. Expert authors contribute to the journal by annotating and highlighting the most significant papers from the extensive body of research published annually, offering valuable insights and saving time for readers by distilling key findings. COCEBI is part of the Current Opinion and Research (CO+RE) suite of journals, which leverages the legacy of editorial excellence, high impact, and global reach to ensure that the journal is a widely read resource integral to scientists' workflow. It is published by Elsevier, a publisher known for its commitment to excellence in scientific publishing and the communication of reproducible biomedical research aimed at improving human health. The journal's content is designed to be an invaluable resource for a diverse audience, including researchers, lecturers, teachers, professionals, policymakers, and students.
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