{"title":"利用原子分辨率电子显微镜对非平衡态随机过程进行高速成像和定量分析","authors":"Takayuki Nakamuro","doi":"10.1093/bulcsj/uoae082","DOIUrl":null,"url":null,"abstract":"\n Chemical phenomena are inherently complex and stochastic, making them difficult to fully understand using conventional ensemble-averaged analytical methods. These methods primarily capture long-lived species and common structural features, limiting the study of transient intermediates and minute structural characteristics. In contrast, single-molecule time-resolved analysis using advanced microscopy techniques, particularly transmission electron microscopy (TEM), offers high spatial and temporal resolution to observe the nonequilibrium dynamics of molecules and their assemblies. This account discusses the authors’ research on developing TEM techniques to visualize intricate and transient interactions within molecular systems, enhancing the understanding of chemical phenomena at atomic and molecular levels.","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"High-Speed Imaging and Quantitative Analysis of Non-Equilibrium Stochastic Processes Using Atomic-Resolution Electron Microscopy\",\"authors\":\"Takayuki Nakamuro\",\"doi\":\"10.1093/bulcsj/uoae082\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n Chemical phenomena are inherently complex and stochastic, making them difficult to fully understand using conventional ensemble-averaged analytical methods. These methods primarily capture long-lived species and common structural features, limiting the study of transient intermediates and minute structural characteristics. In contrast, single-molecule time-resolved analysis using advanced microscopy techniques, particularly transmission electron microscopy (TEM), offers high spatial and temporal resolution to observe the nonequilibrium dynamics of molecules and their assemblies. This account discusses the authors’ research on developing TEM techniques to visualize intricate and transient interactions within molecular systems, enhancing the understanding of chemical phenomena at atomic and molecular levels.\",\"PeriodicalId\":9511,\"journal\":{\"name\":\"Bulletin of the Chemical Society of Japan\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of the Chemical Society of Japan\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1093/bulcsj/uoae082\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Chemical Society of Japan","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1093/bulcsj/uoae082","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
化学现象本身具有复杂性和随机性,因此难以用传统的集合平均分析方法完全理解。这些方法主要捕捉长寿命物种和常见结构特征,限制了对瞬时中间产物和微小结构特征的研究。相比之下,利用先进的显微镜技术,特别是透射电子显微镜(TEM)进行单分子时间分辨分析,可提供高空间和时间分辨率,观察分子及其组装体的非平衡动态。这篇文章讨论了作者在开发 TEM 技术方面的研究,这些技术可将分子系统内错综复杂的瞬时相互作用可视化,从而加深对原子和分子水平化学现象的理解。
High-Speed Imaging and Quantitative Analysis of Non-Equilibrium Stochastic Processes Using Atomic-Resolution Electron Microscopy
Chemical phenomena are inherently complex and stochastic, making them difficult to fully understand using conventional ensemble-averaged analytical methods. These methods primarily capture long-lived species and common structural features, limiting the study of transient intermediates and minute structural characteristics. In contrast, single-molecule time-resolved analysis using advanced microscopy techniques, particularly transmission electron microscopy (TEM), offers high spatial and temporal resolution to observe the nonequilibrium dynamics of molecules and their assemblies. This account discusses the authors’ research on developing TEM techniques to visualize intricate and transient interactions within molecular systems, enhancing the understanding of chemical phenomena at atomic and molecular levels.
期刊介绍:
The Bulletin of the Chemical Society of Japan (BCSJ) is devoted to the publication of scientific research papers in the fields of Theoretical and Physical Chemistry, Analytical and Inorganic Chemistry, Organic and Biological Chemistry, and Applied and Materials Chemistry. BCSJ appears as a monthly journal online and in advance with three kinds of papers (Accounts, Articles, and Short Articles) describing original research. The purpose of BCSJ is to select and publish the most important papers with the broadest significance to the chemistry community in general. The Chemical Society of Japan hopes all visitors will notice the usefulness of our journal and the abundance of topics, and welcomes more submissions from scientists all over the world.