用两种剂量的 A 型肉毒杆菌毒素治疗原发性腋窝多汗症--观察性研究

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-07-16 DOI:10.3390/toxins16070320
María Jesús Antón Andrés, Ernesto Domingo Candau Pérez, María Pilar Bermejo de la Fuente
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引用次数: 0

摘要

多汗症(HH)的定义是出汗量超过其体温调节功能所需的量,对患者的生活质量产生负面影响,并干扰其社交、工作和家庭生活。因此,本研究旨在评估在每个腋窝注射两种不同剂量的 A 型肉毒毒素(50 或 100 单位)对严重原发性腋窝多汗症的疗效。研究对象为转诊至我科的31名严重原发性腋窝多汗症患者,其中一些患者在随访期间接受了不止一次浸润治疗,共进行了82次治疗。多汗症的严重程度采用多汗症疾病严重程度量表(HDSS)进行评估,生活质量采用皮肤科生活质量指数(DLQI)问卷进行评估。奥那保妥适A浸润疗法减轻了多汗症的严重程度,改善了患者的生活质量,两组之间无显著差异。
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Treatment of Primary Axillary Hyperhidrosis with Two Doses of Botulinum Toxin A—Observational Study
Hyperhidrosis (HH) is defined as the production of more sweat than is necessary for its thermoregulatory function, negatively affecting patients’ quality of life and interfering with their social, work and family life. In this context, the aim of thisstudy was to evaluate the efficacy of two different doses of botulinum toxin type A (50 or 100 units) in each axilla in severe primary axillary hyperhidrosis. A descriptive, observational, cross-sectional and post-authorisation study was conducted onpatients referred to our department.Thirty-one patients with severe primary axillary hyperhidrosis were included, some of whom received more than one infiltration during the follow-up period, performing a total of 82 procedures. They were assigned by simple random sampling to two types of treatment: infiltration of 50 or 100 units (U) of botulinum toxin A per axilla.Hyperhidrosis severity was assessed using the Hyperhidrosis Disease Severity Scale (HDSS), and quality of life was assessed using the Dermatology Life Quality Index (DLQI) questionnaire. Onabotulinum toxin A infiltration reduced the severity of hyperhidrosis and improved the quality of life of the treated patients, with no significant differences between the two groups.
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7.20
自引率
4.30%
发文量
567
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