研究视神经炎患者的视神经特征

Supriya B N, Divya Prasad, Srinivas Phani Nakkella
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摘要

视神经炎是一种视神经自身免疫性脱髓鞘疾病。它可以是特发性的/感染后的/多发性硬化症的组成部分。它通常与其他系统性疾病无关。它导致炎症,影响视神经的髓鞘内膜。本研究旨在确定一家三级医疗中心视神经炎患者的视神经特征。通过考虑决定视神经功能的特定成分,对 30 名视神经炎患者进行了描述性研究。研究的视神经组成部分包括视力、色觉、对比度、视野、视觉诱发电位和磁共振成像(MRI)。女性患视神经炎的比例高于男性(66.6%)。最常见的年龄组是 26-35 岁(36.6%)。50%的患者(15 例)出现瞳孔相对传入缺损(RAPD)。视力下降主要发生在手部运动之间--手指靠近脸部数数(40%)。所有患者都存在色觉缺陷,其中以红绿色觉缺陷最为常见。30%的患者视野严重缺损。83% 的患者核磁共振成像正常。视神经炎通常影响青壮年。正确诊断疾病、适时治疗是非常必要的。需要与神经科医生联合治疗,让他们了解疾病的过程、治疗方法和预防复发。
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To study the optic nerve characteristics in patients with optic neuritis
Optic neuritis is defined as an autoimmune demyelinating disorder of the optic nerve. It can be idiopathic/post infectious/component of multiple sclerosis. It is not associated with other systemic diseases so commonly. It causes inflammation, which affects the myelin lining of the optic erve. Aim of this study was to identify study the optic nerve characteristics in patients with optic neuritis in a tertiary care center. A descriptive study was done on 30patients with optic neuritis, by considering specific components that determine the optic nerve function. Components of optic nerve studied includes, visual acuity, color vision, contrast ensitivity, visual fields, visual evoked otential and magnetic resonance imaging (MRI). Optic neuritis is more common in females than males (66.6%). Most common age group is 26-35years (36.6%). Relative afferent pupillary defect (RAPD) seen in 50% of patients (15pts). Visual acuity loss majority in between hand movements–counting fingers close to face (40%). Color vision defects were present in all the patients, Red-Green color defect was more common. Visual fields showed severely depressed fields in 30% patients. MRI was normal in 83% patients. Optic neuritis usually affects young adults. Proper diagnosis of the disease, correct treatment at right time is necessary. Combined approach for treatment with neurologist is required to make them aware of disease process, treatment & to prevent recurrences.
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