病例报告:一名急性淋巴细胞白血病成人患者的 18F-FDG PET/CT 骨骼超扫描成像

Yu Hu, Wenli Dai, Peng Wang, Yawen Feng, Hui Feng, Jun Li
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摘要

我们在此描述了一例罕见的成人急性淋巴细胞白血病病例,该病例具有 18F-氟脱氧葡萄糖(18F-FDG)正电子发射断层扫描/计算机断层扫描(PET/CT)骨骼超扫描样表现。骨髓摄取的程度非常高,远远超过了大脑生理性摄取和放射活动的水平。其分布与骨骼闪烁扫描所见的超扫描极为相似。18F-FDG PET/CT 的骨骼超扫描在血液病、伴有广泛骨转移的实体瘤和代谢性疾病中均有报道。因此,我们回顾了所报道病例的 PET/CT 图像,发现分布较为均匀、无原发肿瘤且下颌骨和颅骨有特异性活动的病例可能提示为血液病。
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Case report: 18F-FDG PET/CT skeletal superscan-like in an adult patient with acute lymphoblastic leukemia
We herein describe a rare case of adult acute lymphoblastic leukemia with an 18florine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) skeletal superscan-like appearance. The degree of bone marrow uptake was so intense that it far exceeded the level of physiological cerebral uptake and radiourinary activity. The distribution was remarkably similar to a superscan seen on skeletal scintigraphy. Skeletal superscans of 18F-FDG PET/CT have been reported in hematological diseases, solid tumors with extensive bone metastasis, and metabolic diseases. Thus, we reviewed the PET/CT images of cases reported, indicating that more homogeneous distribution, without primary tumor and specific mandibular and skull activity, may be suggestive of hematological diseases.
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