卵巢生长畸胎瘤综合征:病例报告和文献综述

Jiaying Tao, Zhixian Shi, Mulan Li, Tingting Li
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摘要

生长畸胎瘤综合征(GTS)是一种继发于恶性生殖细胞肿瘤的罕见病症。其特点是化疗期间或化疗后腹部肿块增大,肿瘤标志物正常,组织病理学显示有成熟畸胎瘤成分。人们对 GTS 的认识有限,常常误认为是疾病进展或复发。这种误诊会导致治疗延误和并发症风险增加。因此,早期发现 GTS 对避免不必要的系统治疗和减轻经济负担至关重要。GTS 对化疗或放疗无反应,完全手术切除是唯一的治疗策略。在本报告中,我们介绍了一例因未成熟畸胎瘤而接受治疗的 20 岁女性 GTS 病例,并回顾了相关文献,旨在丰富我们对 GTS 临床表现的认识。
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Growing teratoma syndrome of the ovary: a case report and literature review
Growing teratoma syndrome (GTS) is a rare condition that arises secondary to malignant germ cell tumors. It is characterized by an enlarging abdominal mass during or after chemotherapy, normal tumor markers, and histopathological indications of mature teratoma components. Awareness of GTS is limited, and it is often mistaken for disease progression or recurrence. This misdiagnosis can lead to delayed treatment and increased risk of complications. Therefore, early identification of GTS is crucial to avoid unnecessary systemic treatments and reduce financial burden. GTS is unresponsive to chemotherapy or radiotherapy and complete surgical resection is the sole therapeutic strategy. In this report, we present a case of GTS in a 20-year-old female following treatment for immature teratoma, alongside a review of the relevant literature aimed at enriching our insight into the clinical manifestations of GTS.
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