COVID-19 对肾脏的长期影响不明显。文献综述

V. A. Fedulkina, A. A. Artamonova
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引用次数: 0

摘要

COVID-19 对慢性肾脏病(CKD)病程的影响已被世界各地的研究人员证实。基本上,在研究 COVID-19 对肾脏的损害时,作者们关注的是新型冠状病毒感染对现有 CKD 患者,尤其是接受血液透析或移植肾脏的患者急性肾损伤(AKI)的发生或死亡率,并对死亡率、风险和预测进行了分析。然而,目前还没有关于这种感染如何影响在 COVID-19 之前没有 CKD 症状的肾脏功能的公开描述。目前,专门分析此类患者长期观察和治疗结果的研究尤其缺乏。本综述考察了国内外关于慢性肾脏疾病对冠状病毒感染严重程度的影响以及 COVID-19 后发生肾脏疾病(包括急性肾损伤)的风险和长期风险的研究。这种方法可以强调在 COVID-19 患者中及时发现早期发展中的慢性肾脏病患者,以便对其进行进一步随访和及时处方肾保护疗法的重要性。在PubMed、Science Direct和eLibrary上使用关键词 "冠状病毒"、"COVID-19"、"SARS-CoV-2"、"急性肾损伤"、"慢性肾脏病 "及其组合搜索文献资料,涵盖2019年至2023年的俄文和英文出版物。
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Unobvious long-term effects of COVID-19 for kidneys. The literature review
The impact of COVID-19 on the course of chronic kidney disease (CKD) has already been confirmed by researchers around the world. Basically, studying kidney damage in COVID-19, the authors pay attention to the new coronavirus infection in terms of the development of acute kidney injury (AKI) or mortality from it in patients with existing CKD, especially patients receiving hemodialysis or having a transplanted kidney, providing an analysis of mortality, risks and forecasts. However, there is still no published description of how this infection can affect the function of kidneys that did not have signs of CKD before COVID-19. Currently, studies devoted to the analysis of long-term results of observation and treatment of such patients are especially scarce. The review examines foreign and domestic studies concerning both the influence of chronic kidney disease on the severity of coronavirus infection and the risks of developing kidney disease after COVID-19, including the development of acute kidney injury and in the long term. This approach can highlight the relevance of timely identification of patients with developing CKD in the early stages among patients with COVID-19 for the purpose of their further follow-up and timely prescription of nephroprotective therapy. The search for literature sources was carried out using PubMed, Science Direct, eLibrary using the keywords “coronavirus”, “COVID-19”, “SARS-CoV-2”, “acute kidney injury”, “chronic kidney disease” and their combinations covering publications from 2019 to 2023 in Russian and English.
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