{"title":"彩色多普勒超声参数作为精子发生和不育症预测指标的作用","authors":"Pranab Patnaik, Sameer Trivedi, Deepak Shaw","doi":"10.22159/ajpcr.2024v17i7.51109","DOIUrl":null,"url":null,"abstract":"Objective: Androgens target the testicular arteries, which may be aberrant in men who are infertile. One of the fastest and most accurate ways to measure testicular blood flow is by color Doppler ultrasonography (CDUS), which combines anatomical and velocity data. The goal of this research is to determine whether testicular artery end-diastolic velocity (EDV), peak systolic velocity (PSV), and resistive index (RI) can be used to differentiate between various types of dyspermia.\nMethods: This was a prospective observational study. In total, 90 patients were enrolled in the study which includes 27 patients with nonobstructive azoospermia (NOA), 19 patients with oligospermia (OL), 24 with obstructive azoospermia (OA), and 20 in the control group having normal sperm count and recent paternity. We compared variables such as EDV, PSV, RI, bilateral testicular volume, testosterone, and follicle-stimulating hormone among different dyspermic groups with the control group.\nResults: The mean age of the study participants was 31.5 years. PSV and RI in the NOA and OL groups were significantly lower compared to the control groups while the OA group was comparable with the control group. With respect to EDV, we observed a significantly lower value only in the NOA group compared to the control group. Significantly lower mean testicular volume and higher follicle-stimulating hormone levels were observed in the NOA group.\nConclusion: Investigating male infertility can be challenging, but CDUS might be very helpful. When used routinely in clinical settings, the RI and PSV can be trustworthy markers for identifying infertility or dyspermic males, especially distinguishing between obstructive and unobstructive azoospermia.","PeriodicalId":8528,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ROLE OF COLOR DOPPLER ULTRASONOGRAPHIC PARAMETER AS A PREDICTOR OF SPERMATOGENESIS AND INFERTILITY\",\"authors\":\"Pranab Patnaik, Sameer Trivedi, Deepak Shaw\",\"doi\":\"10.22159/ajpcr.2024v17i7.51109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: Androgens target the testicular arteries, which may be aberrant in men who are infertile. One of the fastest and most accurate ways to measure testicular blood flow is by color Doppler ultrasonography (CDUS), which combines anatomical and velocity data. The goal of this research is to determine whether testicular artery end-diastolic velocity (EDV), peak systolic velocity (PSV), and resistive index (RI) can be used to differentiate between various types of dyspermia.\\nMethods: This was a prospective observational study. In total, 90 patients were enrolled in the study which includes 27 patients with nonobstructive azoospermia (NOA), 19 patients with oligospermia (OL), 24 with obstructive azoospermia (OA), and 20 in the control group having normal sperm count and recent paternity. We compared variables such as EDV, PSV, RI, bilateral testicular volume, testosterone, and follicle-stimulating hormone among different dyspermic groups with the control group.\\nResults: The mean age of the study participants was 31.5 years. PSV and RI in the NOA and OL groups were significantly lower compared to the control groups while the OA group was comparable with the control group. With respect to EDV, we observed a significantly lower value only in the NOA group compared to the control group. Significantly lower mean testicular volume and higher follicle-stimulating hormone levels were observed in the NOA group.\\nConclusion: Investigating male infertility can be challenging, but CDUS might be very helpful. When used routinely in clinical settings, the RI and PSV can be trustworthy markers for identifying infertility or dyspermic males, especially distinguishing between obstructive and unobstructive azoospermia.\",\"PeriodicalId\":8528,\"journal\":{\"name\":\"Asian Journal of Pharmaceutical and Clinical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Pharmaceutical and Clinical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22159/ajpcr.2024v17i7.51109\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Pharmaceutical and Clinical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22159/ajpcr.2024v17i7.51109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:雄激素以睾丸动脉为目标,而不育男性的睾丸动脉可能出现异常。测量睾丸血流的最快、最准确的方法之一是彩色多普勒超声成像(CDUS),它结合了解剖学和速度数据。本研究的目的是确定睾丸动脉舒张末期速度(EDV)、收缩峰值速度(PSV)和阻力指数(RI)是否可用于区分各种类型的精子生成障碍:这是一项前瞻性观察研究。共有 90 名患者参与了这项研究,其中包括 27 名非梗阻性无精子症(NOA)患者、19 名少精子症(OL)患者、24 名梗阻性无精子症(OA)患者,以及 20 名精子数量正常且近期有父子关系的对照组患者。我们比较了不同精子生成障碍组和对照组的 EDV、PSV、RI、双侧睾丸体积、睾酮和卵泡刺激素等变量:研究对象的平均年龄为 31.5 岁。与对照组相比,NOA 组和 OL 组的 PSV 和 RI 明显较低,而 OA 组与对照组相当。在EDV方面,我们观察到只有NOA组的数值明显低于对照组。NOA组的平均睾丸体积明显较低,卵泡刺激素水平较高:结论:对男性不育症的调查可能具有挑战性,但 CDUS 可能会很有帮助。在临床上常规使用时,RI 和 PSV 可作为识别男性不育或精子生成障碍的可靠标记,尤其是区分梗阻性和非梗阻性无精子症。
ROLE OF COLOR DOPPLER ULTRASONOGRAPHIC PARAMETER AS A PREDICTOR OF SPERMATOGENESIS AND INFERTILITY
Objective: Androgens target the testicular arteries, which may be aberrant in men who are infertile. One of the fastest and most accurate ways to measure testicular blood flow is by color Doppler ultrasonography (CDUS), which combines anatomical and velocity data. The goal of this research is to determine whether testicular artery end-diastolic velocity (EDV), peak systolic velocity (PSV), and resistive index (RI) can be used to differentiate between various types of dyspermia.
Methods: This was a prospective observational study. In total, 90 patients were enrolled in the study which includes 27 patients with nonobstructive azoospermia (NOA), 19 patients with oligospermia (OL), 24 with obstructive azoospermia (OA), and 20 in the control group having normal sperm count and recent paternity. We compared variables such as EDV, PSV, RI, bilateral testicular volume, testosterone, and follicle-stimulating hormone among different dyspermic groups with the control group.
Results: The mean age of the study participants was 31.5 years. PSV and RI in the NOA and OL groups were significantly lower compared to the control groups while the OA group was comparable with the control group. With respect to EDV, we observed a significantly lower value only in the NOA group compared to the control group. Significantly lower mean testicular volume and higher follicle-stimulating hormone levels were observed in the NOA group.
Conclusion: Investigating male infertility can be challenging, but CDUS might be very helpful. When used routinely in clinical settings, the RI and PSV can be trustworthy markers for identifying infertility or dyspermic males, especially distinguishing between obstructive and unobstructive azoospermia.