I Goesti Ngoerah Gde Ngoerah 教授综合医院缺血性脑卒中患者血脂谱与住院时间和临床结果的相关性

Pande Kadek, Putri Rahayu Indrayani, Wayan Putu, Sutirta Yasa, Anak Agung, Wiradewi Lestari, Nyoman Wande
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摘要

缺血性中风是由于脑动脉或静脉阻塞,导致脑血流和供氧中断而引起的神经系统疾病。缺血性中风的原因之一是血脂异常。本研究旨在确定血脂谱与缺血性中风患者的住院时间和临床预后之间的相关性。本研究为横断面研究,使用的二手数据来自 I Goesti Ngoerah Gde Ngoerah 教授综合医院在 2021 年 1 月 1 日至 2023 年 1 月 31 日期间收治的符合纳入和排除标准的缺血性中风患者。在 215 名研究对象中,137 名(63.7%)为男性,78 名为女性。此外,192 人(89.3%)的年龄在 45 岁以下。45岁,23人(10.7%)小于45岁。斯皮尔曼分析显示,住院时间与总胆固醇水平(r = 0.174,p = 0.010)、低密度脂蛋白(r = 0.152,p = 0.026)和高密度脂蛋白(r = 0.141,p = 0.039)呈弱负相关,但与甘油三酯水平(r = 0.020,p = 0.767)无显著相关。该研究结果还表明,临床结果与总胆固醇(p = 0.029)和低密度脂蛋白(p = 0.039)相关,但与甘油三酯水平(p = 0.090)和高密度脂蛋白(p = 0.115)不相关。然而,要确定血脂状况与缺血性脑卒中患者住院时间和临床预后之间的直接相关性,还需要采用队列方法进行进一步研究。关键词:缺血性中风 住院时间 结果
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The Correlation Between Lipid Profiles with Length of Stay and Clinical Outcomes of Ischemic Stroke Patients at Prof. Dr. I Goesti Ngoerah Gde Ngoerah General Hospital
Ischemic stroke is a neurological condition due to the blockage of cerebral arteries or veins, leading to disrupted blood flow and oxygen supply to the brain. One of the causes of ischemic stroke is abnormalities in lipid profile levels. This study aims to determine the correlation between lipid profiles with the length of stay and clinical outcomes in patients with ischemic stroke. This study is cross-sectional research using secondary data from ischemic stroke patients admitted to Prof. Dr. I Goesti Ngoerah Gde Ngoerah General Hospital between January 1, 2021, and January 31, 2023, who meet the inclusion and exclusion criteria. Out of 215 study subjects included in this research, 137 (63.7%) were male, and 78 were female. Additionally, 192 (89.3%) were aged ? 45 years, and 23 (10.7%) were <45 years. Spearman's analysis showed a weak negative correlation between the length of stay and total cholesterol levels (r = 0.174, p = 0.010), LDL (r = 0.152, p = 0.026), and HDL (r = 0.141, p = 0.039), but no significant correlation was found with triglyceride levels (r = 0.020, p = 0.767). The results of this study also indicated a correlation between clinical outcomes and total cholesterol (p = 0.029) and LDL (p = 0.039), but not with triglyceride levels (p = 0.090) and HDL (p = 0.115). However, further research with a cohort method is needed to establish a direct correlation between lipid profiles with length of stay and clinical outcomes in ischemic stroke patients. Keywords : Ischemic Stroke, Length of Stay, Outcome
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