基于离散马尔可夫链与随机微分方程的神经活动数值模拟

Erhui Wang, Xuefei Luan
{"title":"基于离散马尔可夫链与随机微分方程的神经活动数值模拟","authors":"Erhui Wang, Xuefei Luan","doi":"10.1088/1742-6596/2791/1/012061","DOIUrl":null,"url":null,"abstract":"\n With the development of new numerical calculation methods and computer software science and technology, people can have a good understanding of the potential mechanisms of cerebrovascular diseases. Here, we combine the stochastic differential equation (SDE) of discrete Markov chains to numerically simulate the dynamic changes of neural signals, and find that the changes of neural signals exhibit regular fluctuations. By analyzing the variation of voltage over time, we know that the voltage change at the next moment is closely related to the previous moment and has continuity. Based on the knowledge of neural ion channel dynamics, it was found that there will be longer peak changes in voltage, exhibiting a power-law distribution, which is consistent with the actual situation and statistical data related to resignation channels. By analyzing the voltage and peak changes of ion channels, we can gain a new understanding of the transmission laws of neural information and greatly improve the biological mechanisms.","PeriodicalId":506941,"journal":{"name":"Journal of Physics: Conference Series","volume":"10 12","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Numerical simulation of neural activity based on discrete Markov chains with stochastic differential equations\",\"authors\":\"Erhui Wang, Xuefei Luan\",\"doi\":\"10.1088/1742-6596/2791/1/012061\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n With the development of new numerical calculation methods and computer software science and technology, people can have a good understanding of the potential mechanisms of cerebrovascular diseases. Here, we combine the stochastic differential equation (SDE) of discrete Markov chains to numerically simulate the dynamic changes of neural signals, and find that the changes of neural signals exhibit regular fluctuations. By analyzing the variation of voltage over time, we know that the voltage change at the next moment is closely related to the previous moment and has continuity. Based on the knowledge of neural ion channel dynamics, it was found that there will be longer peak changes in voltage, exhibiting a power-law distribution, which is consistent with the actual situation and statistical data related to resignation channels. By analyzing the voltage and peak changes of ion channels, we can gain a new understanding of the transmission laws of neural information and greatly improve the biological mechanisms.\",\"PeriodicalId\":506941,\"journal\":{\"name\":\"Journal of Physics: Conference Series\",\"volume\":\"10 12\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Physics: Conference Series\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1088/1742-6596/2791/1/012061\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Physics: Conference Series","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1088/1742-6596/2791/1/012061","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

随着新的数值计算方法和计算机软件科学技术的发展,人们可以很好地了解脑血管疾病的潜在机制。在此,我们结合离散马尔可夫链的随机微分方程(SDE),对神经信号的动态变化进行数值模拟,发现神经信号的变化呈现出有规律的波动。通过分析电压随时间的变化,我们知道下一时刻的电压变化与上一时刻密切相关,具有连续性。根据神经离子通道动力学的知识,发现电压会有较长的峰值变化,呈现幂律分布,这与辞职通道的实际情况和相关统计数据是一致的。通过分析离子通道的电压和峰值变化,我们可以对神经信息的传递规律有新的认识,大大完善生物机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Numerical simulation of neural activity based on discrete Markov chains with stochastic differential equations
With the development of new numerical calculation methods and computer software science and technology, people can have a good understanding of the potential mechanisms of cerebrovascular diseases. Here, we combine the stochastic differential equation (SDE) of discrete Markov chains to numerically simulate the dynamic changes of neural signals, and find that the changes of neural signals exhibit regular fluctuations. By analyzing the variation of voltage over time, we know that the voltage change at the next moment is closely related to the previous moment and has continuity. Based on the knowledge of neural ion channel dynamics, it was found that there will be longer peak changes in voltage, exhibiting a power-law distribution, which is consistent with the actual situation and statistical data related to resignation channels. By analyzing the voltage and peak changes of ion channels, we can gain a new understanding of the transmission laws of neural information and greatly improve the biological mechanisms.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
LPI radar waveform recognition model based on multiple feature image and quasi-residual attention module About the 3D virtualization of the Millikan oil drop experiment Study on the characteristics of the bypass flow field of the net structure under different Reynolds number conditions Exploring the Universe through Gamma-Ray Astronomy: Characterization and Performance of the LST-1 Telescope Analysis of structural dynamic response of vertical sound barriers under natural wind and vehicle induced pulsating wind effects
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1