维生素 D 对 COVID-19 患者的治疗作用

Q3 Nursing Clinical Nutrition Open Science Pub Date : 2024-07-16 DOI:10.1016/j.nutos.2024.07.004

Muhammad Imran , Ramna Zia , Maryam Ali , Saima Sadaf , Kiran Iqbal , Asad Ali , Usama Iqbal , Sana Muhammad Din , Jawaria Shahid , Ali Ahsan , Zahra Kalim , Chaudhry Ahmed Shabbir , Sajjad Ullah

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引用次数: 0

摘要

SARS-CoV-2 在全球范围内产生了重大影响，导致广泛的疾病和死亡。由于缺乏特异性抗病毒治疗方法，人们越来越有兴趣探索包括维生素 D 在内的各种营养补充剂的潜在治疗效果。维生素 D 在健康中发挥着重要作用，被认为可以调节免疫反应和减少炎症，这可能对预防和治疗 2019 年冠状病毒疾病（COVID-19）有影响。维生素 D 水平低的患者容易出现严重后果。维生素 D 与 COVID-19 呈反比关系。本综述旨在了解维生素D对COVID-19的补救作用，包括其潜在的作用机制、临床研究证据以及对COVID-19患者补充维生素D的建议。

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Therapeutic role of vitamin D in COVID-19 patients

SARS-CoV-2 has had a significant worldwide impact, leading to widespread illness and mortality. With the lack of specific antiviral treatments, there is a growing interest in exploring the potential therapeutic effects of various nutritional supplements, including vitamin D. Vitamin D plays an essential role in health, has been implicated in modulating the immune response and reducing inflammation, which may have implications in the prevention and management of coronavirus disease 2019 (COVID-19). Patients having low level of vitamin D are predisposed to severe consequences. Vitamin D and COVID-19 have shown an inverse relationship. This review is an understanding of the remedial effects of vitamin D in COVID-19, including its potential mechanism of action, evidence from clinical studies, and recommendations for supplementation of vitamin D in patients suffering from COVID-19.