白藜芦醇通过引发自噬和抑制 mTOR 通路对大鼠 2 型糖尿病有改善作用。

L. A. Mohammed, Ahmed Medhat Hegazy, W. E. El gazzar, N. El-shaer, Heba Bayoumi, Salwa A. Elgendy, Heba A. Elnoury, H. E. Nasr
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引用次数: 0

摘要

背景:影响数百万人的 2 型糖尿病(T2DM)已成为严重的健康问题:2型糖尿病(T2DM)影响着数百万人,已成为一个严重的健康问题。哺乳动物雷帕霉素靶标(mTOR)的过度激活是自噬的负面参与,事实上可能有助于β细胞功能的丧失。
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Ameliorative effect of resveratrol against type 2 diabetes in rats through triggering of autophagy and inhibition of mTOR pathway.
Background: Type 2 diabetes mellitus (T2DM), which affects millions of individuals, has become a serious health problem.The mammalian target of rapamycin (mTOR) hyperactivation is a negatively involved autophagy that may in fact aid in the loss of β -cell function.Resveratrol (RSV) is a naturally occurring phytoalexin, mostly found incereals, fruits
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