{"title":"经导管二尖瓣边缘对边缘修补术治疗患有多发性肌炎的年轻女性的严重心力衰竭：病例报告","authors":"Masayoshi Fujii MD, Tetsuari Onishi MD, PhD, Hiroyuki Yamamoto MD, PhD, Nobuyuki Takahashi MD, Tomofumi Takaya MD, PhD, Hiroya Kawai MD, PhD, FJCC","doi":"10.1016/j.jccase.2024.06.001","DOIUrl":null,"url":null,"abstract":"<div><p><span><span><span>Polymyositis (PM) and </span>dermatomyositis (DM) are chronic inflammatory muscle disorders characterized by </span>muscle weakness and fatigue. They are histopathologically defined by </span>inflammatory cell<span><span> infiltrates in the skeletal muscle<span>. In a recent meta-analysis, the incidence of cardiovascular complications in patients with PM/DM ranged from 9 to 72 %, with heart failure being the most commonly reported heart disease. In cases of heart failure accompanied by severe </span></span>mitral regurgitation<span> that is refractory due to guideline-directed medical therapy, the transcatheter edge-to-edge mitral valve repair (TEER) procedure using the MitraClip (Abbott Vascular, Santa Clara, CA, USA) offers an alternative therapeutic approach. We present a pioneering case report describing the successful application of TEER in a young woman with drug-refractory heart failure due to cardiovascular involvement in PM.</span></span></p></div><div><h3>Learning objective</h3><p></p><ul><li><span>•</span><span><p><span>In polymyositis (PM)/ dermatomyositis (DM), the most commonly reported clinical heart disorder is heart failure, with some cases attributed to </span>mitral regurgitation.</p></span></li><li><span>•</span><span><p>Patients suffering from systemic inflammatory diseases such as PM/DM often face high surgical risk, and the MitraClip is an effective treatment modality.</p></span></li></ul></div>","PeriodicalId":52092,"journal":{"name":"Journal of Cardiology Cases","volume":"30 3","pages":"Pages 90-93"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transcatheter edge-to-edge mitral valve repair for severe heart failure in a young woman with polymyositis: A case report\",\"authors\":\"Masayoshi Fujii MD, Tetsuari Onishi MD, PhD, Hiroyuki Yamamoto MD, PhD, Nobuyuki Takahashi MD, Tomofumi Takaya MD, PhD, Hiroya Kawai MD, PhD, FJCC\",\"doi\":\"10.1016/j.jccase.2024.06.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span><span>Polymyositis (PM) and </span>dermatomyositis (DM) are chronic inflammatory muscle disorders characterized by </span>muscle weakness and fatigue. They are histopathologically defined by </span>inflammatory cell<span><span> infiltrates in the skeletal muscle<span>. In a recent meta-analysis, the incidence of cardiovascular complications in patients with PM/DM ranged from 9 to 72 %, with heart failure being the most commonly reported heart disease. In cases of heart failure accompanied by severe </span></span>mitral regurgitation<span> that is refractory due to guideline-directed medical therapy, the transcatheter edge-to-edge mitral valve repair (TEER) procedure using the MitraClip (Abbott Vascular, Santa Clara, CA, USA) offers an alternative therapeutic approach. We present a pioneering case report describing the successful application of TEER in a young woman with drug-refractory heart failure due to cardiovascular involvement in PM.</span></span></p></div><div><h3>Learning objective</h3><p></p><ul><li><span>•</span><span><p><span>In polymyositis (PM)/ dermatomyositis (DM), the most commonly reported clinical heart disorder is heart failure, with some cases attributed to </span>mitral regurgitation.</p></span></li><li><span>•</span><span><p>Patients suffering from systemic inflammatory diseases such as PM/DM often face high surgical risk, and the MitraClip is an effective treatment modality.</p></span></li></ul></div>\",\"PeriodicalId\":52092,\"journal\":{\"name\":\"Journal of Cardiology Cases\",\"volume\":\"30 3\",\"pages\":\"Pages 90-93\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cardiology Cases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1878540924000574\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiology Cases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878540924000574","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Transcatheter edge-to-edge mitral valve repair for severe heart failure in a young woman with polymyositis: A case report
Polymyositis (PM) and dermatomyositis (DM) are chronic inflammatory muscle disorders characterized by muscle weakness and fatigue. They are histopathologically defined by inflammatory cell infiltrates in the skeletal muscle. In a recent meta-analysis, the incidence of cardiovascular complications in patients with PM/DM ranged from 9 to 72 %, with heart failure being the most commonly reported heart disease. In cases of heart failure accompanied by severe mitral regurgitation that is refractory due to guideline-directed medical therapy, the transcatheter edge-to-edge mitral valve repair (TEER) procedure using the MitraClip (Abbott Vascular, Santa Clara, CA, USA) offers an alternative therapeutic approach. We present a pioneering case report describing the successful application of TEER in a young woman with drug-refractory heart failure due to cardiovascular involvement in PM.
Learning objective
•
In polymyositis (PM)/ dermatomyositis (DM), the most commonly reported clinical heart disorder is heart failure, with some cases attributed to mitral regurgitation.
•
Patients suffering from systemic inflammatory diseases such as PM/DM often face high surgical risk, and the MitraClip is an effective treatment modality.
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