揭示草药药妆在抗衰老和皮肤老化相关疾病中的作用。

IF 1.6 4区 医学 Q3 OPHTHALMOLOGY Cutaneous and Ocular Toxicology Pub Date : 2024-09-01 Epub Date: 2024-07-23 DOI:10.1080/15569527.2024.2380326
Prashant Kumar, Anurag Verma, Sumel Ashique, Mithun Bhowmick, Sourav Mohanto, Anita Singh, Madhu Gupta, Abhishek Gupta, Tanweer Haider
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引用次数: 0

摘要

皮肤老化是一种自然生理现象,其特点是随着时间的推移出现皱纹、老年斑、皮肤松弛和干燥。皮肤在外貌吸引力中的重要性与日俱增,这加剧了人们对护肤的关注。抗衰老化妆品在滋养皮肤、提高皮肤质量和促进整体健康方面发挥着举足轻重的作用。如今,化妆品已经超越了单纯的美学范畴,成为个人健康不可或缺的一部分。当代人对永葆青春的追求不断加强,促使人们对皮肤老化过程进行更深入的探索。本研究全面探讨了皮肤老化所涉及的各种因素,包括干细胞和内皮细胞等细胞、血管、软组织和信号通路。文章结合相关动物模型,仔细研究了皮肤老化的分子基础,包括活性氧、受损 DNA、自由基、离子和蛋白质(mRNA)等生化因素。文章批判性地分析了利用中草药成分的结果,强调了它们的抗衰老优势。文章简明扼要地论述了导致皮肤老化的因素、机理观点、涉及草药药妆的管理方法以及相关并发症(尤其是心血管疾病、帕金森氏症、老年痴呆症等)。此外,该手稿还进一步总结了草药药妆在抗衰老和衰老相关疾病方面的最新专利创新和毒性。尽管取得了进展,但要充分挖掘草药成分作为抗衰老剂的潜力,进一步的研究势在必行。
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Unlocking the role of herbal cosmeceutical in anti-ageing and skin ageing associated diseases.

The process of skin ageing is a natural biological phenomenon characterised by the emergence of wrinkles, age spots, sagging skin, and dryness over time. The increasing significance of skin in physical attractiveness has heightened skincare concerns. Anti-ageing cosmetics play a pivotal role in nurturing the skin, enhancing its quality, and promoting overall health. Today, cosmetics have evolved beyond mere aesthetics and are now integral to individual wellness. The contemporary quest for perpetual youth has intensified, prompting a deeper exploration into the skin ageing process. This comprehensive exploration delves into various elements involved in skin ageing, encompassing cells such as stem and endothelial cells, blood vessels, soft tissues, and signalling pathways. The molecular basis of skin ageing, including biochemical factors like reactive oxygen species, damaged DNA, free radicals, ions, and proteins (mRNA), is scrutinised alongside relevant animal models. The article critically analyzes the outcomes of utilising herbal components, emphasising their advantageous anti-ageing properties. The factors contributing to skin ageing, mechanistic perspectives, management approaches involving herbal cosmeceutical, and associated complications (especially cardiovascular diseases, Parkinson's, Alzheimer's, etc.) are succinctly addressed. In addition, the manuscript further summarises the recent patented innovations and toxicity of the herbal cosmeceuticals for anti-ageing and ageing associated disorders. Despite progress, further research is imperative to unlock the full potential of herbal components as anti-ageing agents.

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来源期刊
CiteScore
3.30
自引率
6.20%
发文量
40
审稿时长
1 months
期刊介绍: Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures. In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.
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