{"title":"牛数字皮炎皮损中的噬菌体生长刺激因子","authors":"Rathanon Khemgaew , Kaoru Hori , Satomi Sasaki , Naoaki Misawa , Takako Taniguchi","doi":"10.1016/j.anaerobe.2024.102882","DOIUrl":null,"url":null,"abstract":"<div><p>Bovine digital dermatitis (BDD) is an infectious skin disease of the hoof characterized by painful ulcerations that cause lameness in dairy cattle. Cell-free supernatants (CFS) of <em>Falsiporphyromonas endometrii</em> predominantly isolated from BDD lesions had the highest growth-stimulating effect on <em>Treponema phagedenis</em> among BDD-associated bacteria. Butyric acid was detected at a concentration of 45.4 mM in CFS of <em>F. endometrii</em>, and the growth of <em>T. phagedenis</em> was significantly promoted by butyric acid supplementation.</p></div>","PeriodicalId":8050,"journal":{"name":"Anaerobe","volume":"88 ","pages":"Article 102882"},"PeriodicalIF":2.5000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The growth-stimulating factor of Treponema phagedenis from bovine digital dermatitis lesions\",\"authors\":\"Rathanon Khemgaew , Kaoru Hori , Satomi Sasaki , Naoaki Misawa , Takako Taniguchi\",\"doi\":\"10.1016/j.anaerobe.2024.102882\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Bovine digital dermatitis (BDD) is an infectious skin disease of the hoof characterized by painful ulcerations that cause lameness in dairy cattle. Cell-free supernatants (CFS) of <em>Falsiporphyromonas endometrii</em> predominantly isolated from BDD lesions had the highest growth-stimulating effect on <em>Treponema phagedenis</em> among BDD-associated bacteria. Butyric acid was detected at a concentration of 45.4 mM in CFS of <em>F. endometrii</em>, and the growth of <em>T. phagedenis</em> was significantly promoted by butyric acid supplementation.</p></div>\",\"PeriodicalId\":8050,\"journal\":{\"name\":\"Anaerobe\",\"volume\":\"88 \",\"pages\":\"Article 102882\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anaerobe\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1075996424000659\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaerobe","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1075996424000659","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
牛数字皮炎(BDD)是一种蹄部传染性皮肤病,其特点是溃疡疼痛,导致奶牛跛行。在与 BDD 相关的细菌中,主要从 BDD 病变中分离出的子宫内膜法氏囊无细胞上清液(CFS)对噬菌体的生长刺激作用最大。在 F. endometrii 的 CFS 中检测到浓度为 45.4 mM 的丁酸,丁酸补充剂显著促进了噬菌体的生长。
The growth-stimulating factor of Treponema phagedenis from bovine digital dermatitis lesions
Bovine digital dermatitis (BDD) is an infectious skin disease of the hoof characterized by painful ulcerations that cause lameness in dairy cattle. Cell-free supernatants (CFS) of Falsiporphyromonas endometrii predominantly isolated from BDD lesions had the highest growth-stimulating effect on Treponema phagedenis among BDD-associated bacteria. Butyric acid was detected at a concentration of 45.4 mM in CFS of F. endometrii, and the growth of T. phagedenis was significantly promoted by butyric acid supplementation.
期刊介绍:
Anaerobe is essential reading for those who wish to remain at the forefront of discoveries relating to life processes of strictly anaerobes. The journal is multi-disciplinary, and provides a unique forum for those investigating anaerobic organisms that cause infections in humans and animals, as well as anaerobes that play roles in microbiomes or environmental processes.
Anaerobe publishes reviews, mini reviews, original research articles, notes and case reports. Relevant topics fall into the broad categories of anaerobes in human and animal diseases, anaerobes in the microbiome, anaerobes in the environment, diagnosis of anaerobes in clinical microbiology laboratories, molecular biology, genetics, pathogenesis, toxins and antibiotic susceptibility of anaerobic bacteria.